Renal drugs Flashcards
1
Q
what is sevelamer? What is it used for? When is it contraindicated?
A
A phosphate binder. Binds phosphates in the gut to reduce absorption of phosphates. This is used in chronic renal failure where you have hyperphosphatemia. Contraindicated in bowel obstruction
2
Q
how do we manage anaemia of chronic renal failure?
A
use a synthetic EPO such as Darbepoetin alfa. Contraindicated in uncontrolled hypertension
3
Q
3 drugs that can lead to acute renal failure- aka the triple whammy?
A
NSAIDs –> reduce prostaglandin production required to dilate afferent arteriole
ACE inhibitor –> reduce Ang2 production required to constrict efferent arteriole
Diuretic
