Renal and Acid/Base Physiology - Parameters

Question 1

Renal Blood Flow (RBF):

Answer 1

1200-1300 mL

Question 2

Renal Plasma Flow (RPF):

Answer 2

600-700 mL

Question 3

Glomerular Filtration Rate (GFR):

Answer 3

120 ml/min

Question 4

Filtration Fraction (FF):

Answer 4

GFR/RPF=FF

120/600 = 0.2

Question 5

Hydrostatic Pressures of Glomerular Capillaries (Pgc):

at Afferent end and Efferent end

Answer 5

Pgc:
Afferent: +53 mmHg
Efferent: +51 mmHg

Question 6

Oncotic Pressures of Glomerular Capillaries (πgc):

at Afferent end and Efferent end

Answer 6

πgc:
Afferent: -26 mmHg
Efferent: -33 mmHg

Question 7

Hydrostatic Pressures of Bowman’s Space (Pbs):

at Afferent end and Efferent end

Answer 7

Pbs:
Afferent: -12 mmHg
Efferent: -12 mmHg

Question 8

Oncotic Pressures of Bowman’s Space (πbs):

at Afferent end and Efferent end

Answer 8

πbs: No proteins cross to the Bowman’s Space!
Afferent: 0 mmHg
Efferent: 0 mmHg

Question 9

Net Filtration Pressure (NFP):

at Afferent end and Efferent end

Answer 9

Net Filtration Pressure:
Afferent: +15 mmHg
Efferent: +6 mmHg
(Sum of πbs, Pbs, πgc, Pgc)

Question 10

Osmotic Concentration in Proximal Tubule:

Answer 10

300 mOsm

Question 11

Maximum rate of transepithelial transport of Glucose:

Answer 11

375 mg/min

Question 12

Osmotic Concentration in interstitium of Cortex:

Answer 12

300 mOsm

Question 13

Urine volume after maximal Concentration:

Answer 13

0.5 L/Day

Question 14

Urine osmolarity after maximal Concentration:

Answer 14

1200 mOsm/L

Question 15

Urine volume after maximal Dilution:

Answer 15

12L/ Day

Question 16

Urine osmolarity after maximal Dilution:

Answer 16

50 mOsm/ Day

Question 17

Maximal osmotic concentration in inner medulla interstitium and its composition:

Answer 17

1200 mOsm: Half of it thanks to Urea and the other Half thanks to Sodium.

Question 18

Blood pH

Answer 18

7.35-7.45

Question 19

PaCO2

Answer 19

38-42 mmHg

Question 20

Standard Bicarbonate

Answer 20

23-25 mM

Question 21

Actual Bicarbonate

Answer 21

23-25 mM

Question 22

Base Buffer

Answer 22

44-49 mEq/L

Question 23

Base Excess

Answer 23

+/-2.5 mEq/L