Renal and Acid/Base Physiology - Parameters Flashcards
Renal Blood Flow (RBF):
1200-1300 mL
Renal Plasma Flow (RPF):
600-700 mL
Glomerular Filtration Rate (GFR):
120 ml/min
Filtration Fraction (FF):
GFR/RPF=FF
120/600 = 0.2
Hydrostatic Pressures of Glomerular Capillaries (Pgc):
at Afferent end and Efferent end
Pgc:
Afferent: +53 mmHg
Efferent: +51 mmHg
Oncotic Pressures of Glomerular Capillaries (πgc):
at Afferent end and Efferent end
πgc:
Afferent: -26 mmHg
Efferent: -33 mmHg
Hydrostatic Pressures of Bowman’s Space (Pbs):
at Afferent end and Efferent end
Pbs:
Afferent: -12 mmHg
Efferent: -12 mmHg
Oncotic Pressures of Bowman’s Space (πbs):
at Afferent end and Efferent end
πbs: No proteins cross to the Bowman’s Space!
Afferent: 0 mmHg
Efferent: 0 mmHg
Net Filtration Pressure (NFP):
at Afferent end and Efferent end
Net Filtration Pressure:
Afferent: +15 mmHg
Efferent: +6 mmHg
(Sum of πbs, Pbs, πgc, Pgc)
Osmotic Concentration in Proximal Tubule:
300 mOsm
Maximum rate of transepithelial transport of Glucose:
375 mg/min
Osmotic Concentration in interstitium of Cortex:
300 mOsm
Urine volume after maximal Concentration:
0.5 L/Day
Urine osmolarity after maximal Concentration:
1200 mOsm/L
Urine volume after maximal Dilution:
12L/ Day
Urine osmolarity after maximal Dilution:
50 mOsm/ Day
Maximal osmotic concentration in inner medulla interstitium and its composition:
1200 mOsm: Half of it thanks to Urea and the other Half thanks to Sodium.
Blood pH
7.35-7.45
PaCO2
38-42 mmHg
Standard Bicarbonate
23-25 mM
Actual Bicarbonate
23-25 mM
Base Buffer
44-49 mEq/L
Base Excess
+/-2.5 mEq/L
