Renal Flashcards
1
Q
Bendeoflumethazide, Indapamide, Chlortalidone: mechanism of action
A
Thiazides diuretics
Inhibit Na/Cl transporter at the DCT and CD
Increases Na, Cl and water excretion
2
Q
Bendroflumethazide, Indapamide, Chlortalidone: indications
A
Hypertension
Oedema of cardiac, renal, hepatic, iatrogenic origin
3
Q
Bendroflumethazide, Indapamide, Chlortalidone: adverse effects
A
Hypokalaemia Hypomagnesaemia Hyponatraemia Hypercalcaemia Hyperuricaemia Reduced glucose tolerance Hypersensitivity
4
Q
Furosemide, Bumetanide, Torasemide: mechanism of action
A
Loop diuretics
Antagonise Na-K-2Cl symporter on thick ascending loop of henle
Increase secretion of Na, K, Cl and water
5
Q
Furosemide, Bumetanide, Torasemide: indications
A
HTN Hyperkaaemia Heart failure Cirrhosis of liver (fluid retention, ascites) Nephrotic syndrome
