Renal Flashcards

1
Q

Renin - Regulation, production, effect

A
  • B1 input, Low BP, Low Na
  • JG cells
  • Angiotensinogen -> AT1
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2
Q

Aldosterone - reg, prod, effect

A
  • AT2
  • Adrenal cortex
    • Up Na via principal cell channel & pump
    • Down K and H
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3
Q

ADH - reg, prod, effect

A
  • AT2
  • Posterior pituitary
  • Aquaporins in Distal collecting duct
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4
Q

ANP - reg, prod, effect

A
  • Cardio distention
  • Heart
  • Up GFR & Na filtration, no Na reabsorption
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5
Q

NSAIDs effect on kidney

A

Inhibit renal PG, constrict afferent arteriole, Down GFR

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6
Q

FF equation

A
  • FF = GFR/RPF = creatinine/PAH

- normal FF=0.2

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7
Q

Winter’s formula

A

P.CO2 = 1.5(HCO3) + 8 +/- 2

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8
Q

K levels affecting ECG (low, high)

A

low - U waves, flattened T waves
high - wide QRS, peaked T waves
arrhythmias in both

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9
Q

Hypercalcemia clinical (4)

A

Stones - kidney
Bones - pain
Groans - abdominal pain
Overtones - psychiatric instability

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10
Q

Hyperkalemia causes (6)

A

DO Insulin LAB

  • Digitalis
  • hyperOsmolatiry
  • insulin deficiency
  • Lysis of cells
  • Acidosis
  • B-adrenergic antagonist
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11
Q

Hypokalemia cause

A

Insulin (stimulate Na/K pump)

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