Renal Flashcards
Type 2 RPGN (immune complex)
Post-infectious
SLE
HSP
Type III RPGN (Pauci-Immune)
ANCA
EM: uniform and diffuse effacement of epithelial foot processes
Minimal change disease
Uniform diffuse thickening of the capillary wall. Foot process effacement
Spike and dome appearance.
Membranous glumerulopathy
Drug that can cause membranous glumerulopathy
Penicillamine
Most common nephritic syndrome in children
PSGN
Most common nephrotic syndrome in children
Minimal change
Most common nephrotic syndrome in adults
FSGS
Most common GN overall
IgA
Most common cause of ARF
ATN
Most common cause of CRF
DM
Hyper-cellular glomeruli, increased mesangial matrix, and thickened GBM with “Double-contour” or “tram-track appearance.
Membranoproliferative
MPGN with ribbon-like pattern on EM
Type II MPGN
Sclerosis of a portion of the glomeruli tuft in some glomeruli
Focal Segmental Glomerulosclerosis
Location of IgA deposits in IgA nephropathy
Mesangium
Treatment of IgA nephropathy
Fish oil
Hereditary syndrome of isolated hematuria with defective GBM synthesis d/t abnromal collagen type IV production
(+) hearing loss
Alport syndrome
Abnormal collagen type in Alport Syndrome
Type IV
Hallmark Of ESRD
Chronic glumerulonephritis
Most common cause of CGN
FSGS
RPGN
Most common and severe type of lupus nephropathy. (+) wire loop lesions
Type IV: Diffuse proliferative GN
IgA deposits in the mesangium associated with purpuric skin lesions on the extremities
Henoch-schonlein purpupra
Most common cause of chronic pyelonephritis in childhood
Reflux nephropathy
Characteristic of analgesic nephropathy
Papillary necrosis
Chronic TI nephritis