Pathology Of Infections Flashcards

1
Q

Vitamin that has shown to reduce the severity of measles infection

A

Vitamin A

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2
Q

Multi-nucleated giant cells seen in measles

A

Warthin-Finkeldey cells

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3
Q

Whitish ulcerated oral muscosal lesions near the opening of Stensen ducts

A

Koplik spots

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4
Q

Infection that manifests with blotchy reddish brown rash on face trunk and proximal extremities

A

Measles

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5
Q

Cowdry type A bodies (Large, pink to purple intranuclear inclusions)

A

Herpes simplex infection

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6
Q

Causes temporal lobe encephalitis

A

Herpes simplex infection

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7
Q

Viral infection that causes sterility

A

Mumps

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8
Q

Centrifugal rash with dewdrop in a rose petal appearance, with dermatomal distribution.

A

Varicella

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9
Q

Facial nerve paralysis with mononuclear infiltration with herpetic intranuclear inclusions

A

Ramsay hunt syndrome

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10
Q

Owl’s eye inclusions

A

Cytomegalovirus infection

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11
Q

Congenital infections that causes blueberry muffin baby

A

CMV
Congenital rubella syndrome
Disseminated neuroblastoma

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12
Q

Drug of choice for CMV infection

A

Ganciclovir

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13
Q

Downey cells

A

Epstein-Barr virus infection

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14
Q

Positive for heterophile antibodies

A

Epstein-Barr Virus infection

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15
Q

Malignancies associated with EBV

A

Burkitt’s lymphoma

Nasopharyngeal CA

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16
Q

Atypical lymphocytes in EBV

A

Downey cells

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17
Q

Causes necrotizing pneumonia complicated by empyema and pneumatocele

A

Staphylococcus aureus infection

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18
Q

Cleaves desmoglein in desmosomes causing separation of the stratum granulosum

A

Exfoliatin

Scalded Skin Syndrome (Ritter disease)

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19
Q

Tumbling motility

A

Listeria monocytogenes

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20
Q

Swarming motility

A

Proteus mirabilis

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21
Q

Shooting star motility

A

Vibrio cholerae

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22
Q

Falling leaf motility

A

Giardia lamblia

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23
Q

Large box-car shaped gram positive extracellular bacteria in chains

A

Bacillus anthracis (Cat 1)

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24
Q

Hemorrhagic, enlarged hilar and peribronchial lymph nodes seen in Bacillus anthracis infection

A

Mediastinal hemorrhage

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25
Q

Slender beaded gram-positive organisms arranged in branching filaments

A

Nocardia asteroides

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26
Q

Modified acid fast stain used to visualize Nocardia asteroides

A

Fite-Faraco

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27
Q

Virulence factor in Bordetella pertussis that causes whooping

A

Tracheal cytotoxin

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28
Q

Organspisms that cause necrotizing pneumonia

A

Staphylococcus aureus
Pseudomomnas aeruginosa
Yersinia pestis
Aspergillus fumigatus

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29
Q

Necrotizing pneumonia with fleur de lis pattern

A

Pseudomonas aeruginosa

30
Q

Ecthyma gangrenosum

A

Pseudomonas aeruginosa

31
Q

Bubonic plague

A

Yersinia pestis

Buboes-enlarged lymph nodes

32
Q

Painful genital ulcer

A

Haemophilus ducreyi

33
Q

Beefy red ulcer with velvety surface and pseudobuboes

A

Klebsiella granulomatis

34
Q

Donovan bodies on Warthin-starry stain

A

Klebsiella granulomatis

35
Q

Most frequent presentation of extrapulmonary tuberculosis

A

Scrofula (lymphadenitis)

36
Q

Most common site of intestinal tuberculosis

A

Ileum

37
Q

Paraspinal “cold” abscess, TB

A

Pott’s disease

38
Q

AIDS patients with CD4

A

Mycobacterium Avium-Intracellulare

39
Q

Enables macrophage to fight off TB

A

IFN-Y

40
Q

Large aggregates of lipid laden macrophages seen in lepromatous leprosy

A

Lepra cells

41
Q

Nerves damaged/involved in lepromatous leprosy

A

Ulnar nerve

Peroneal nerve

42
Q

Manifestations if tertiary syphilis

A

Neurosyphilis
Aortitis
Gummas

43
Q

Manifestations of congenital syphilis

A

Pneumonia alba

Hutchinson teeth

44
Q

Most commoncp cause of urethritis

A
  1. N. Gonorrhoeae

2. C. Trachomatis

45
Q

Most common caus eof epididymitis

A
  1. C. Trachomatis

2. N. Gonorrhoeae

46
Q

Erythema chronicum migrans

A

Borrelia burgdorferi

47
Q

Amount of necrosis disproportionate to number of neutrophils and bacteria

A

Clostridium cellulitits (C. perfringens)

48
Q

Marked edema with myonecrosis, extensive fluid exudates with gas bubbles

A

Clostridial gas gangrene

49
Q

Stellate absces

A

Lymphogranuloma venereum (C. trachomatis)

50
Q

Thick gelatinous capsule, soap bubble lesions.

Yeast grow in the meninges or expand the perivascular Virchow-Robin spaces

A

Cryptococcus neoformans

51
Q

Nonseptate,irregularly wide fungal hyphae with frequent right-angle branching

A

Mucromycosis

52
Q

Spherules in endospores

A

Cocciodes immitis

53
Q

Intracellular yeast

A

Histoplasmosis capsulatum

54
Q

Broad-based bud

A

Blastomyces dermatidis

55
Q

Mariner’s wheel

A

Paracoccidiodes brasilensis

56
Q

Causes cerebral malaria

A

Plasmodium falciparum

57
Q

Durck granulomas

A

Malaria

58
Q

Microcopic dots present in P. vivax and P. ovale

A

Schuffner’s dots

59
Q

Microscopic dots seen in P. falciparum

A

Maurer’s dots

60
Q

Microscopic dots seen in P. malariae

A

Ziemann’s dots

61
Q

Drug of choice for radical cure of benign tertian malaria

A

Primaquin

62
Q

Maltese cross pattern

Intraerythrocytic ring-shaped trophozoit s in tetrwds

A

Babesia microti

63
Q

Tryponoma brucci

A

African sleeping sickness

64
Q

Mott cells

A

Trypanoma brucci

65
Q

Nurse cells

A

Trichinella spiralis

66
Q

Encysts in striated skeletal muscles with rich blood supply

A

Trichinella spiralis

67
Q

Seen in filariasis, tropicalmpulmonary eosinophilia. dead microfilariae surrounded by stellate hyaline eosinophilic precipitates embedded in small epithelioid granulomas

A

Meyer-kouvenaar bodies

68
Q

River blindness

A

Onchoceca volvulus

Tx: ivermectin

69
Q

Complication thwt may arise during initiation of treatment due to lysis of onchocercal worms

A

Mazzoti reaction

70
Q

Potentially fatal neurologic complication of measles that can be prevented by vaccination

A

Subacute sclerosing pancpencephalitis