Pathology Of Infections Flashcards

1
Q

Vitamin that has shown to reduce the severity of measles infection

A

Vitamin A

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2
Q

Multi-nucleated giant cells seen in measles

A

Warthin-Finkeldey cells

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3
Q

Whitish ulcerated oral muscosal lesions near the opening of Stensen ducts

A

Koplik spots

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4
Q

Infection that manifests with blotchy reddish brown rash on face trunk and proximal extremities

A

Measles

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5
Q

Cowdry type A bodies (Large, pink to purple intranuclear inclusions)

A

Herpes simplex infection

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6
Q

Causes temporal lobe encephalitis

A

Herpes simplex infection

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7
Q

Viral infection that causes sterility

A

Mumps

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8
Q

Centrifugal rash with dewdrop in a rose petal appearance, with dermatomal distribution.

A

Varicella

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9
Q

Facial nerve paralysis with mononuclear infiltration with herpetic intranuclear inclusions

A

Ramsay hunt syndrome

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10
Q

Owl’s eye inclusions

A

Cytomegalovirus infection

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11
Q

Congenital infections that causes blueberry muffin baby

A

CMV
Congenital rubella syndrome
Disseminated neuroblastoma

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12
Q

Drug of choice for CMV infection

A

Ganciclovir

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13
Q

Downey cells

A

Epstein-Barr virus infection

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14
Q

Positive for heterophile antibodies

A

Epstein-Barr Virus infection

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15
Q

Malignancies associated with EBV

A

Burkitt’s lymphoma

Nasopharyngeal CA

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16
Q

Atypical lymphocytes in EBV

A

Downey cells

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17
Q

Causes necrotizing pneumonia complicated by empyema and pneumatocele

A

Staphylococcus aureus infection

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18
Q

Cleaves desmoglein in desmosomes causing separation of the stratum granulosum

A

Exfoliatin

Scalded Skin Syndrome (Ritter disease)

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19
Q

Tumbling motility

A

Listeria monocytogenes

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20
Q

Swarming motility

A

Proteus mirabilis

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21
Q

Shooting star motility

A

Vibrio cholerae

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22
Q

Falling leaf motility

A

Giardia lamblia

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23
Q

Large box-car shaped gram positive extracellular bacteria in chains

A

Bacillus anthracis (Cat 1)

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24
Q

Hemorrhagic, enlarged hilar and peribronchial lymph nodes seen in Bacillus anthracis infection

A

Mediastinal hemorrhage

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25
Slender beaded gram-positive organisms arranged in branching filaments
Nocardia asteroides
26
Modified acid fast stain used to visualize Nocardia asteroides
Fite-Faraco
27
Virulence factor in Bordetella pertussis that causes whooping
Tracheal cytotoxin
28
Organspisms that cause necrotizing pneumonia
Staphylococcus aureus Pseudomomnas aeruginosa Yersinia pestis Aspergillus fumigatus
29
Necrotizing pneumonia with fleur de lis pattern
Pseudomonas aeruginosa
30
Ecthyma gangrenosum
Pseudomonas aeruginosa
31
Bubonic plague
Yersinia pestis | Buboes-enlarged lymph nodes
32
Painful genital ulcer
Haemophilus ducreyi
33
Beefy red ulcer with velvety surface and pseudobuboes
Klebsiella granulomatis
34
Donovan bodies on Warthin-starry stain
Klebsiella granulomatis
35
Most frequent presentation of extrapulmonary tuberculosis
Scrofula (lymphadenitis)
36
Most common site of intestinal tuberculosis
Ileum
37
Paraspinal "cold" abscess, TB
Pott's disease
38
AIDS patients with CD4
Mycobacterium Avium-Intracellulare
39
Enables macrophage to fight off TB
IFN-Y
40
Large aggregates of lipid laden macrophages seen in lepromatous leprosy
Lepra cells
41
Nerves damaged/involved in lepromatous leprosy
Ulnar nerve | Peroneal nerve
42
Manifestations if tertiary syphilis
Neurosyphilis Aortitis Gummas
43
Manifestations of congenital syphilis
Pneumonia alba | Hutchinson teeth
44
Most commoncp cause of urethritis
1. N. Gonorrhoeae | 2. C. Trachomatis
45
Most common caus eof epididymitis
1. C. Trachomatis | 2. N. Gonorrhoeae
46
Erythema chronicum migrans
Borrelia burgdorferi
47
Amount of necrosis disproportionate to number of neutrophils and bacteria
Clostridium cellulitits (C. perfringens)
48
Marked edema with myonecrosis, extensive fluid exudates with gas bubbles
Clostridial gas gangrene
49
Stellate absces
Lymphogranuloma venereum (C. trachomatis)
50
Thick gelatinous capsule, soap bubble lesions. | Yeast grow in the meninges or expand the perivascular Virchow-Robin spaces
Cryptococcus neoformans
51
Nonseptate,irregularly wide fungal hyphae with frequent right-angle branching
Mucromycosis
52
Spherules in endospores
Cocciodes immitis
53
Intracellular yeast
Histoplasmosis capsulatum
54
Broad-based bud
Blastomyces dermatidis
55
Mariner's wheel
Paracoccidiodes brasilensis
56
Causes cerebral malaria
Plasmodium falciparum
57
Durck granulomas
Malaria
58
Microcopic dots present in P. vivax and P. ovale
Schuffner's dots
59
Microscopic dots seen in P. falciparum
Maurer's dots
60
Microscopic dots seen in P. malariae
Ziemann's dots
61
Drug of choice for radical cure of benign tertian malaria
Primaquin
62
Maltese cross pattern | Intraerythrocytic ring-shaped trophozoit s in tetrwds
Babesia microti
63
Tryponoma brucci
African sleeping sickness
64
Mott cells
Trypanoma brucci
65
Nurse cells
Trichinella spiralis
66
Encysts in striated skeletal muscles with rich blood supply
Trichinella spiralis
67
Seen in filariasis, tropicalmpulmonary eosinophilia. dead microfilariae surrounded by stellate hyaline eosinophilic precipitates embedded in small epithelioid granulomas
Meyer-kouvenaar bodies
68
River blindness
Onchoceca volvulus Tx: ivermectin
69
Complication thwt may arise during initiation of treatment due to lysis of onchocercal worms
Mazzoti reaction
70
Potentially fatal neurologic complication of measles that can be prevented by vaccination
Subacute sclerosing pancpencephalitis