Renal Flashcards
What are the consequences of renal failure? (think mnemonic…)
MAD HUNGER
- Metabolic Acidosis
- Dyslipidemis
- Hyperkalemia
- Uremia
- Na/H2O retention
- Growth retardation/developmental delay
- Erythropoietin failure (anemia)
- Renal osteodystrophy
What common associations cause Ca Oxalate crystals?
- ethylene glycol
- Crohn’s
- Vit C
What common associations cause Cystine cyrstals?
Prob with metabolism of the following: COLA
- cysteine
- ornithine
- lysine
- arginine
Wire looping of capillaries in glomerulus means what dz?
diffuse proliferative glomerulonephritis
Most common cause of death in SLE is what?
diffuse proliferative glomerulonephritis
Subendothelial & sometimes intramembranous IgG & C3 deposition characterize what dz?
diffuse proliferative glomerulonephritis
increased anti-DNAase B titers characterize what glomerular dz?
acute poststreptococcal glomerulonephritis
Defect in alpha intercalated cells to secrete H+:
- Dz name?
- Common causes?
- consequence?
- Type 1 renal tubular acidosis (pH>5.5)
- amphotericin B, analgesics, congenital
- hypokalemia, up risk calcium phosphate kidney stones
Defect in promial tubule HCO3 reabsorption:
- Dz name?
- Common causes?
- consequence?
- Type 2 renal tubular acidosis (pH <5.5)
- Fanconi syndrome, chemicals, carbonic anhydrase inhibitors, multiple myeloma (light chains)
- hypokalemia, hypophasphatemic rickets
Hypoaldosteronism can produce renal tubular acidosis.:
- Dz name?
- Common causes?
- consequence?
- Type 4 renal tubular acidosis (pH<5.5)
- high aldosterone or K-sparing diuretics
- hyperkalemia
GFR equation?
U inulin * V / P inulin = Clearance inulin = GFR
ERPF equation?
U pah * V / P pah = Clearance pah= ERPF (underestimates true by 10%)
Filtered fraction equation?
GFR/RPF
Filtered load equation?
GFR * Px
Excretion rate equation?
V * Ux
