Renal Flashcards
Functional unit of the kidney and is responsible for maintenance of body fluid homeostasis
Nephron
-within the Bowman’s capsule
-site of filtration
Glomerular capillary bed
-surrounds the nephron tube
-returns reabsorbed substances to systemic circulation
-secretes substances into interstitial space
Peritubular capillary bed
-Hollow structure lined with epithelial cells (tight junctions between cells)
-Site of reabsorption & secretion
Nephron tubule component
Four basic Renal processes:
F
R
S
E
Filtration
Reabsorption
Secretion
Excretion
The _______ consists of most substances dissolved in plasma
Does not include ________ & ______ _____
filtrate
Proteins (some small peptide hormones are)
Blood Cells
-1st step in the process that ultimately leads to the formation of urine by the kidneys
-Involves movement of water and solutes from the plasma into the Bowman’s Space
Filtration
Selectivity of glomerular filtration barrier is crucial for renal function Is based on:
Molecular Size
Electrical Charge
________ ___________ is the process that moves a substance out the tubular lumen across the epithelial layer
Tubular Reabsorption
-Movement across/through (trans) the apical membrane into the epithelial cells
-Can remain inside the epithelial cell or move out across the basolateral membrane to enter the interstitial fluid Paracellular Movement
Transcellular
Movement between/beside (para) cells through the tight junctions into interstitial fluid
Paracellular movement