Renal Flashcards

1
Q

Renal blood flow is equal to ……. ml/min

A

1200

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2
Q

kidneys account for how much of body mass?

A

0.5%

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3
Q

what are the 2 types of nephrons?

A

cortical & juxtamedullary

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4
Q

how many nephrons in the body?

A

1-1.25 million

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5
Q

what is the most numerous nephron type?

A

cortical: 80-85% of all nephrons

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6
Q

What is the purpose of the renal corpsucle?

A

filtration

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7
Q

What is the purpose of the renal tubule?

A

reabsorption & secretion

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8
Q

what sort of capillaries are in the glomerulus?

A

fenestrated capillaries

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9
Q

what is the purpose of podocytes?

A

they cover the fenestrated capillaries and only allow H20 & small solutes to pass

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10
Q

where does filtration begin?

A

in the capsular space

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11
Q

why does the proximal tubule aid in high reabsorption?

A
  • simple cuboidal epithelium
  • microvilli= increase SA
  • increased diffusion rate`
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12
Q

Where does 100% of glucose + proteins reabsorb?

A

Proximal Tubule

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13
Q

Where is 65% of water/ion reabsorbed?

A

Proximal tubule

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14
Q

what is the final section of the kidney tubule?

A

distal tubule

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15
Q

Where does 20% H20 water absorption occur?

A

Nephron loop- facilitated by simple squamous epithelium

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16
Q

The three layers of the ureter:

A

1) Inner mucosa
2) muscularis
3) adventita

17
Q

How much volume does the urinary bladder hold?

A

700-800ml- highly distensible

18
Q

What 3 pressures drive net filtration?

A

1) Glomerular Blood Hydrostatic Pressure- most significant 55mmHg (need to keep this UP to MAINTAIN BLOOD FLOW)
2) Capsular Hydrostatic Pressure (CHP)
3) Blood Colloid Osmotic Pressure (BCOP)

19
Q

GBHP forces fluid …… glomerulus capillary

A

out of

20
Q

CHP ….. fluid from exiting the glomerulus capillaries

A

resists

21
Q

BCOP ….. fluid loss in the capsular space

A

opposes

22
Q

How much filtrate ( L) is produced per day for males and females?

A

males= 180L p/day = 125ml/min
females= 150L p/day= 105ml/min

23
Q

In regards to the myogenic mechanism, constricting the AFFERENT arteriole will …. GFR

A

decrease

24
Q

In regards to the myogenic mechanism, constricting the EFFERENT arteriole will … GFR

A

increase

25
Q

In regards to the myogenic mechanism, dilating the AFFERENT arteriole will …. GFR

A

increase

26
Q

In regards to the myogenic mechanism, dilating the EFFERENT arteriole will …. GFR

A

decrease

27
Q

Angiotensin II vaso…… to ….. GFR

A

vasoconstricts, reduce

28
Q

Proximal Tubule does/ doesn’t possess microvilli?

A

does

29
Q

the descending limb is ….. to water.

A

permeable

30
Q

The ascending limb has a …. wall which …………. water passage.

A

thick, does not aid

31
Q

What 2 cells are distinct in the late section of the Distant Convoluted Tubule?

A

1) Principle cells: reabsorb Na and K
2) Intercalated cells: secrete H+/ reabsorb HC03