Immune Flashcards
most abundant WBC
Neutrophils - 70%
Eosinophils are granulocytes packaged with ….. enzymes. Their key role is to defende against: ……..
digestive, parasitic worms
Basophils contain: h…… & h…….
histamine and heparin
Dendritic cells are known for having ……. arms
long
(they are antigen catchers)
Natural Killer cells are cytotoxic against ….. cells
cancer
What do natural killer cells lack?
specific antigen receptors
B cells mature in the
bone marrow
T cells mature in the
thymus
The thymus is bi-lobed. it sits behind the sternum
Natural killer cells initiate cell destruction via:
apoptosis
Lymphocytes recognise …….. antigens
specific
what is present on the surface of B cells or secreted by B cells?
Immunglobulin (IgE)
What co-receptor molecule corresponds with cytotoxic T-cells?
CD8
What co-receptor molecule corresponds with Helper T-cells?
CD4
What is the structure of lymphoid tissue?
Reticular connective tissue
Primary lymphatic organs are
the site where lymphocytes mature and develop
secondary lymphatic organs are
where antigens are recognised and activated
How many lymph nodes are present in the body?
600
What is the largest lymphoid organ?
The spleen
What are the two regions of the spleen? Briefly describe.
1) Red pulp: vascular sinuses filled with RBC & macrophages
2) White pulp: lymphocytes on reticular fibres.
3 main purposes of the spleen:
- clean blood of defective/old blood cells. Macrophages engulf debris
- recycle iron from RBC to make haemoglobin
- store monocytes & platelets
Locate three regions where there is mucous membranes
Tonsils, Peyers patches (wall of intestine), appendix
process where phagocytes squeeze through capillary wall to attend to injured tissue is called
diapedesis
process where cells are attracted to a site of injury along chemical gradients is called
chemotaxis
process where injured cells release factors that INCREASE WBC is called:
leukocytosis
process that aids in leukocytes adhering to capillary wall is called;
margination
