Immune

Question 1

most abundant WBC

Answer 1

Neutrophils - 70%

Question 2

Eosinophils are granulocytes packaged with ….. enzymes. Their key role is to defende against: ……..

Answer 2

digestive, parasitic worms

Question 3

Basophils contain: h…… & h…….

Answer 3

histamine and heparin

Question 4

Dendritic cells are known for having ……. arms

Answer 4

long
(they are antigen catchers)

Question 5

Natural Killer cells are cytotoxic against ….. cells

Answer 5

cancer

Question 6

What do natural killer cells lack?

Answer 6

specific antigen receptors

Question 7

B cells mature in the

Answer 7

bone marrow

Question 8

T cells mature in the

Answer 8

thymus

The thymus is bi-lobed. it sits behind the sternum

Question 9

Natural killer cells initiate cell destruction via:

Answer 9

apoptosis

Question 10

Lymphocytes recognise …….. antigens

Answer 10

specific

Question 11

what is present on the surface of B cells or secreted by B cells?

Answer 11

Immunglobulin (IgE)

Question 12

What co-receptor molecule corresponds with cytotoxic T-cells?

Answer 12

CD8

Question 13

What co-receptor molecule corresponds with Helper T-cells?

Answer 13

CD4

Question 14

What is the structure of lymphoid tissue?

Answer 14

Reticular connective tissue

Question 15

Primary lymphatic organs are

Answer 15

the site where lymphocytes mature and develop

Question 16

secondary lymphatic organs are

Answer 16

where antigens are recognised and activated

Question 17

How many lymph nodes are present in the body?

Answer 17

600

Question 18

What is the largest lymphoid organ?

Answer 18

The spleen

Question 19

What are the two regions of the spleen? Briefly describe.

Answer 19

1) Red pulp: vascular sinuses filled with RBC & macrophages
2) White pulp: lymphocytes on reticular fibres.

Question 20

3 main purposes of the spleen:

Answer 20

• clean blood of defective/old blood cells. Macrophages engulf debris
• recycle iron from RBC to make haemoglobin
• store monocytes & platelets

Question 21

Locate three regions where there is mucous membranes

Answer 21

Tonsils, Peyers patches (wall of intestine), appendix

Question 22

process where phagocytes squeeze through capillary wall to attend to injured tissue is called

Answer 22

diapedesis

Question 23

process where cells are attracted to a site of injury along chemical gradients is called

Answer 23

chemotaxis

Question 24

process where injured cells release factors that INCREASE WBC is called:

Answer 24

leukocytosis

Question 25

process that aids in leukocytes adhering to capillary wall is called;

Answer 25

margination