Renal Flashcards

1
Q

What is urinary obstruction

A

Urine flow obstruction

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2
Q

two reasons for urinary obstruction

A
  1. anatomical reason (blockage)
  2. Functional (decrease muscle action)
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3
Q

What occurs from a urinary blockage

A
  • Backs up and accumulation of urine in tract and into kidneys
    = nephron/glomerular dysfunction and damage
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4
Q

S+S of urinary obstruction

A
  • decrease urine flow
  • pain
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5
Q

treatment for urinary obstruction

A

Removal of blockage

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6
Q

What is acute kidney injury

A
  • Occurs when a significant decline in renal function = decrease fluid, electrolyte and PH balance.
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7
Q

What does AKL lead to

A
  • Decrease GFR (decrease 25% or more)
  • Decrease oliguria (decrease urinary output)
  • Azotemia = increase nitrogenous compounds in blood (urea)
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8
Q

What causes AKI

A
  1. Pre-renal (result in kidney injury but doesn’t occur in kidneys)
    e.g. hypovolemia, renal artery stenosis
  2. Intra-renal
    e.g. tubular necrosis, glomerulonephritis, CKD
  3. post-renal
    Urinary tract obstructions
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9
Q

S+S AKI

A
  1. Decrease urination
  2. Oedema
  3. Metabolic acidosis
  4. Effect other systems (nausea and vomiting, irritability, drowsiness, confusion)
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10
Q

AKL Management

A

specific to cause + fluids, electrolytes and increase PH maintenance, possible nutritional Maintenace

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11
Q

What is Glomerulonephritis

A

Inflammation of glomeruli = inadequate glomerular filtration + increase in permeability (more can fit through and less filtration)

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12
Q

S+S Glomerulonephritis

A
  • Protein Uria (protein in urine)
  • Hematuria (blood cells (RBC) in urine)
  • Oliguria
  • Hypertension
  • Oedema
  • Azotemia
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13
Q

What is Acute and chronic Glomerulonephritis

A

Acute :
- mainly due to streptococcal infection
Chronic:
-typically due to other systemic complications

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14
Q

what is Chronic kidney disease (CKD)

A
  • Chronic condition
  • Progressive and irreversible loss of nephrons
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15
Q

pathway of CKD

A
  • decrease glomerular function = decrease GFR
  • Decrease reabsorption
  • Decrease secretion
  • Decrease other functions (BP homeostasis, production of EPO)
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16
Q

What can CKD lead to

A
  • Glomerular hypertension, hyperfiltration and hypertrophy
    = glomerulosclerosis
    = tubular inflammation and fibrosis
    = further nephron loss
17
Q

What causes CKD

A
  • Diabetes
  • Hypertension
  • Glomerulonephritis
  • Polycystic kidney
18
Q

S+S CKD

A
  • Uremia (syndrome of CKD) = Azotemia + systemic S+S
  • By the time S+S occur, nephron loss is too significant