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1
Q

ribosomes bind to

A

cytosolic face of rough endoplasmic reticulum

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2
Q

A transmembrane protein is

A

an integral globular protein

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3
Q

Every cell does not respond to every extracellular signal because

A

every cell has a different combination of receptors

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4
Q

In the production of monoclonal antibodies two cells are fused together to produce a

A

hybridoma

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5
Q

After the sodium-potassium pump has hydrolysed ATP the conformational change causes extracellular binding of

A

extracellular potassium ions

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6
Q

A kinase enzyme adds a phosphate on to the

A

R group of a protein

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7
Q

The affinity of haemoglobin for for oxygen increases with

A

increase in ph and decrease in temp

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8
Q

vital stains only stain

A

dead cells

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9
Q

at isoelectric point, the mass of precipitate does what

A

increases

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10
Q

accuracy means

A

Accuracy refers to how close a measurement is to the true or accepted value

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11
Q

precision means

A

Precision refers to how close measurements of the same item are to each other.

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12
Q

what is catalysed by reverse transcriptase

A

RNA to DNA

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13
Q

The grouse male with other males at leks. what is a characteristic of this species

A

polygamy

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14
Q

what measure is not appropriate for reducing the incidence of disease in refugee camps?

A

improved vector control

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15
Q

cells that produce antibodies are

A

B lymphocytes

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16
Q

sexual imprinting is

A

an irreversible process that occurs in young animals and helps them to survive

17
Q

what is a prosthetic group

A

A prosthetic group is a non-protein unit tightly bound to a protein and necessary for its
function

18
Q

the conformation of tertiary structure is stabilised by

A

interactions between R groups: hydrophobic interactions;

ionic bonds; London dispersion forces; hydrogen bonds; disulfide bridges

19
Q

when do allosteric interactions occur

A

Allosteric interactions occur between spatially distinct sites

20
Q

kinases do what

A

catalyse the transfer of a phosphate group to other proteins

21
Q

phosphatases do what

A

catalyse the removal of a phosphate group from proteins

22
Q

what is a transporter protein

A

Transporter proteins bind to the specific substance to be transported and undergo a
conformational change to transfer the solute across the membrane

23
Q

receptors for hydrophobic signalling molecules are

A

transcription factors

24
Q

examples of hydrophobic signalling molecules

A

steroid hormones eg testosterone and oestrogen

25
Q

hydrophilic signal transduction

A

Transmembrane receptors change conformation when the ligand binds to the extracellular face; the signal molecule does not enter the cell, but the signal is transduced across the plasma membrane
Transmembrane receptors act as signal transducers by converting the extracellular ligandbinding event into intracellular signals, which alters the behaviour of the cell
often involve G-proteins or cascades of phosphorylation by kinase enzymes

26
Q

what is an action potential

A

An action potential is a wave of electrical excitation along a neuron’s plasma membrane

27
Q

The transmission of a nerve impulse requires

A

changes in the membrane potential of the

neuron’s plasma membrane

28
Q

Depolarisation of the plasma membrane as a result of the entry of positive ions triggers _____ and further _____ occurs

A

opening of voltage-gated sodium channels, and further depolarisation occurs

29
Q

after a nerve impulse how is the resting membrane potential restored

A

Inactivation of the sodium channels and the opening of potassium channels restores the
resting membrane potential

30
Q

a wave of excitation is

A

Depolarisation of a patch of membrane causing neighbouring regions of membrane to
depolarise and go through the same cycle, as adjacent voltage-gated sodium channels are
opened

31
Q

what happens when the action potential reaches the end of the neuron

A

vesicles containing
neurotransmitter fuse with the membrane — this releases neurotransmitter, which
stimulates a response in a connecting cell

32
Q

ion concentration gradients are reestablished by

A

sodium potassium pump

33
Q

Assay

A

An assay is an investigative procedure that quantitively measures and qualititively assesses the amount, prescience or function of a target entity.

34
Q

Immunoassay

A

A procedure for detecting specific proteins through their properties as antigens or antibodies

Often fluorescent or colour change if found