Regulation Of Gene Experssion In Eukaryotes

Question 1

A multistep process resulting in the production of a functional gene product: RNA/Protein.

Answer 1

Gene expression

Question 2

Levels of Regulation

Answer 2

– Transcription (Primary site)
– Post-transcription
– Post-translation
– DNA Modification

Question 3

Continually expressed genes

Answer 3

Housekeeping genes

Question 4

• Expressed under certain conditions

* Expressed in tissue/cell specific

Answer 4

Regulated genes

Question 5

Enhance or repress transcription —>

Answer 5

control amount of RNA/Protein produced.

These are done by DNA-proteins interaction

Question 6

• Cis-acting DNA element

Answer 6

Function as transcription enhancers/ silencers.

Question 7

• Trans-acting DNA binding proteins

Answer 7

Function as specific transcription factors: activators/ repressors.

Question 8

The glucocorticoid receptor (GR) regulates genes controlling.

Answer 8

development,
metabolism,
and immune response

Question 9

how 30,000 genes can give rise to over 100,000 proteins. ?

Answer 9

differential splicing.

Splice-site choice

Question 10

Apoprotein (apo) B

Answer 10

An essential protein component of chylomicrons and very low density lipoproteins (VLDL).