RED-s Flashcards

1
Q

What is the primary focus of the podcast on Female Athlete Health?

A

Updates in Relative Energy Deficiency in Sport (RED-S) and improving care for patients

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2
Q

What was the previous name of Relative Energy Deficiency in Sport (RED-S)?

A

Female Athlete Triad

RED-S was changed to be inclusive of both male and female athletes.

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3
Q

What makes up the female athlete triad?

A

Amenorrhea, eating disorders, osteoporosis

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4
Q

What does energy balance (EB) equal in the context of RED-S?

A

Energy Intake (EI) - Energy Output (EO)

When in negative energy balance for
weeks to months, athletes will exhibit
signs/symptoms of REDs

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5
Q

What is REDs?

A

A syndrome of impaired physiological and/or psychological functioning experienced by female and male athletes that is caused by exposure to problematic (prolonged and/or severe) LEA.

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6
Q

What are the detrimental outcomes of Relative Energy Deficiency in Sport (RED-S)?

A

Decreases in:
* Energy metabolism
* Reproductive function
* Musculoskeletal health
* Immunity
* Glycogen synthesis
* Cardiovascular health
* Haematological health

These factors can lead to impaired well-being, increased injury risk, and decreased sports performance.

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7
Q

What is the underlying factor in the syndrome of RED-S?

A

Low energy availability

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8
Q

What percentage of female athletes may be affected by disordered eating?

A

Up to 62%

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9
Q

Is REDs a definite sign of disordered eating?

A

No.

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10
Q

What is the continuum of disordered eating?

A

Balance between appropriate eating and exercise
Ranges from “healthy dieting” to extreme weight loss
Can include clinical eating disorders

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11
Q

What percentage of male and female athletes may be affected by disordered eating?

A

33% of males, 62% of females

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12
Q

One study found the number of college athletes at risk of anorexia or bulimia nervosa to be…

A
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13
Q

Fill in the blank: Anorexia Nervosa is characterized by …

A

Refusal to maintain body weight for age and height.
Intense fear of gaining weight.
Disturbed body image or denial of seriousness of current low body weight.
Amenorrhea.

ie. BMI< 17.5 or < 85% of expected weight

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14
Q

What defines Bulimia Nervosa?

A

Recurrent episodes of binge eating and inappropriate compensatory behavior to prevent weight gain.
Self-evaluation influenced by body image, may occur with or without AN.

Binge eating occurs at least twice a week for three months.

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15
Q

Define binge eating

A

Eating a larger amount of food in a discrete time. Sense of lack of control over eating during episode.

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16
Q

What is menarche?

A

First menstrual cycle

12.5 years average

17
Q

What is amenorrhea?

A

Absence of menstrual cycle lasting more than 3 months

Primary Amenorrhea = delayed menarche (15 yr);
Secondary Amenorrhea occurs after menarche

18
Q

What are the definitions of eumenorrhea and oligomenorrhea?

A

Eumenorrhea: menstrual cycles at intervals near the median (28 days)
Oligomenorrhea: menstrual cycles longer than 35 days, or infrequent menstrual cycle; 3-6/yr

19
Q

Define luteal suppression and anovulation

A

Luteal suppression: a menstrual cycle with a luteal phase
shorter than 11 d in length or with a low concentration of
progesterone.
Anovulation: a menstrual cycle without ovulation.

20
Q

What is the estimated prevalence of primary amenorrhea in athletes?

A

~7% overall; 22% in cheerleading, diving, and gymnastics

21
Q

What can cause menstrual dysfunction in athletes?

A

Low energy intake and high energy expenditure

22
Q

What is the estimated prevalence of secondary amenorrhea in athletes?

A

~2-5% overall in women; 69% in dancers, 65% in long distance runners

23
Q

Menstrual dysfunction can occur after how many months of low energy availability?

A

Can occur in as little as 1 month of low energy availability but more likely 2-3 months. Takes 3-6 months to recover after improvement in energy availability.

24
Q

What is functional hypothalamic amenorrhea?

A

Negative energy balance caused by high EE.

25
What is the definition of Low Bone Mineral Density (BMD)? | aka. Osteopenia
Bone mineral density Z-score between -1.0 and -2.0
26
What is osteoporosis?
Bone mineral density Z-score less than -2.0 with secondary risk factors for fracture (undernutrition, hypoestrogenism, prior fractures)
27
What are causes of low BMD in athletes?
Low energy availability, menstrual dysfunction, and low intake of calcium
28
What does low energy availability cause?
- Low IGF-1 (promotes bone health) - High Cortisol - Perhaps low intake of calcium
29
What is a major determinant of BMD?
Menstrual history: Late menarche, menstrual irregularities or amenorrhea lead to reduced peak BMD, premature bone loss or increased fracture risk
30
What causes undernutrition and hypoestrogen? Define both terms.
Low bone mineral density. Undernutrition: Decrease rate of bone formation Hypoestrogen: Increased bone resorption rate ## Footnote Consequences: Increased risk of fractures and osteoporosis.
31
What is recommended treatment for RED-S?
Seek proper help from a multidisciplinary healthcare team
32
What should energy availability (EA) be increased to for recovery?
More than 30 kcal/kg of Fat-Free Mass (FFM), preferably 45 kcal/kg of FFM
33
What is the recommended daily intake of calcium, protein and vitamin D for those recovering from RED-S?
Ca: 1000-1300 mg/day Vit D: 400-800 IU/d P: 1.2-1.6 g/kg/day
34
How should resistance training change during treatment for REDs?
Decrease overall training by 10-20%, aiming to increase body weight by 2-3%.
35
What percentage reduction in overall training is suggested for recovery?
10-20%
36
What is the potential risk of low energy availability on bone health?
Increased risk of stress fractures and osteoporosis
37
What did the study on exercise and LEA in women find?
Exercise did not suppress the LH pulsatility. LEA reduced LH pulsatility by ~60%. Theoretically can resume menses by eating more while exercising even at high levels?