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Hematology > Red Cell Abnormalies > Flashcards

Red Cell Abnormalies Flashcards

0
Q

Anisocytosis is detected by

A

Making blood smear or by checking patients MCV/RDW

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1
Q

RBC that varies in size

A

Anisocytosis

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2
Q

Diameter of Macrocytosis

A

> 8 um

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3
Q

Majority of RBCs are larger than normal.

A

Macrocytosis

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4
Q

Associated with impaired DNA synthesis.

A

Macrocytosis

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5
Q

Broadfish tapeworm or Diphyllobothrium latum infection

A

Macrocytosis

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6
Q

Glossitis- inflamed tongue

A

Macrocytosis

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7
Q

Diameter of microcytosis

A

<7 um

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8
Q

With wide central pallor

Majority RBC are smaller than normal

A

Microcytosis

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9
Q

Usually associated with detective hgb formation

A

Microcytosis

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10
Q

Usually RBC are hypochromic but can be normochromic

A

Microcytosis

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11
Q

Iron def. anemia and hookworm infection

A

Microcytosis

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12
Q

Spoon shaped nail

A

Koilocychia

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13
Q

Microcytosis can be seen in

A 
Thalassemia
Anemia of chronic dse
Iron deficiency anemia
Lead poisoning
Sideroblastic anemia
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14
Q

Microcytiv rbc’s with wide central pallor

A

Ghost cells

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15
Q

HgB distribution is unequal

A

Anisochromic cells

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16
Q

Central pallor is >1/3 of rbc diameter
Rbc is falsely dec hgb content
Usually microcytic

A

Hypochromic cells

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17
Q

RBCs falsely inc hgb content

A

Hyperchromic crlls

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18
Q

Larger than normal with bluish tinge
Caused by residual rna
Causes: dec. rbc survival, hemorrhage or erthyroid hyperplastic marrow

A

Polychromatophilic Erythrocyte

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19
Q

Residual RNA is stained with what?

A

Supervital stain not with romanosky stain

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20
Q

Rbc that varies in shape

A

Poikilocyte

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21
Q

Normal shape of poikilocyte

A

Biconcave disk; donut shaped without a hole in the middle

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22
Q

Inc rbc flexibility in poikilocyte

A

Concavitt/depression

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23
Q

Spherical in shape
Lacks cp
MCHC is high

A

Spherocytes

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24
Q

Spherocytes is seen in

A

Hemolytic anemia and hereditary spherocytosis

25
Q

Mouth cell

Elongated rbc with slit like cp

A

Stomatocytes

26
Q

Stomatocytes is seen in

A

Rh null syndrome
Alcholism
Severe liver dse
Hereditary stomatocytosis

27
Q

Thorn/spurr cells

Rbcs with irregular spiculated surfacen

A

Acanthocytes

28
Q

Crenated rbc
With regular spiculated surface
Spicules are rounded at tip

A

Echinocytes

29
Q

Echinocytes are seen in

A

Artificial drying of smear
Bile acids abnormalities
Barbiturates
Salicylates

30
Q

Regulary spiculated surface with more pointed top

A

Burr cells

31
Q

Burr cells is seen in

A

Pyruvate kinase def
Uremia
Cancer of stomach
Acute blood loss

32
Q

Other name for ovalocytes

A

Elliptocytes or cigar cells

33
Q

Oval shaped rbc

Found in normal persons

A

Ovalocytes

34
Q

Ovalocytes can be seen in

A

Patient with congenital anemia

35
Q

Other name for dacryocytes

A

Tear drop cell or tennis racket cell

36
Q

Pear shaped rbc

A

Dacryocyte

37
Q

Dacryocytes is seen in

A

Myelofibrosis

Myeloid metaplasia

38
Q

Fragmented rbc

A

Schistocytes

39
Q

Schistocyte is seen in

A

Microangiopathic hemolytic anemia
Uremia
Severe burns
Disseminated intravascular coagulation

40
Q

Other name for sickle cells

A

Drepanocytes

41
Q

Sicke cell or crescent shaped rbc

A

Sickle cell

42
Q

Sickle cells is caused by polymerization of an abnormal hgb called hgb s

A

polymerization of an abnormal hgb called hgb s

43
Q

Sickle cell is found in

A

Sickle cell anemia

44
Q

Other name for target cells

A

Lepatocyte, Platycyte, codocyte, mexican hat cell

45
Q

Target cells is seen in

A

Liver dse and hemoglobinopathies

Thalassemia

46
Q

Irreg basophilic granules

Stain with deep blue with wright’s stain

A

Basophilic Stippling

47
Q

Coarse stippling is seen in

A

Lead poisoning and other dse with impaired hgb synthesis

48
Q

Intraerythrocyte collections of ions

Stained with perfs prussian blue

A

Sideroblastic anemia

49
Q

Round remnants of nuclear chromatin

Dna composition

A

Howell-Jolly bodies

50
Q

Single HJ bodies seen in

A

Megaloblastic anemia

Hemolytic anemia

51
Q

Multiple HJ seen in

A

Megaloblastic anemia

Abnormal erythropoiesis

52
Q

Remnants of mitotic spindle, probably microtubules.
Ring shaped, figure of eight, loop shaped structures
Evidence of abnormal erythropoiesis

A

Cabot rings

53
Q

Cabot rings stained with

A

Red/Reddish purple with wright’s stain

54
Q

Malarial stippling for P.vivax

A

Schuffner’s granules

55
Q

Malarial stippling for P.falcifarum

A

Maurer’s dot

56
Q

Malarial stippling fo P.ovale

A

Schuffner’s granules

57
Q

Malarial stippling for P. Malariae

A

Ziemann’s dot

58
Q

Aggregation of denatured Hgb

A

Heinz bodies

59
Q

Heinz bodies is seen in

A

G6PD deficiency and hereditary hemolytic anemia following use of oxidizing drugs

60
Q

Heinz bodies in irreg refractile granules seen in

A

Periphery of the cell

61
Q

Normal inclusion of heinz bodies

A

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Hematology (6 decks)

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