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Hematology > Quality Assurance > Flashcards

Quality Assurance Flashcards

0
Q

Factors to consider:

A 
Staff
Quality of materials
Methods
Reagents
Pxn/physician satisfaction
Financial cost
Instruments
Reporting of test results
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1
Q

Best possible service
Patient
Physician

A

Quality assurance

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2
Q

Involves the procedures of monitoring and evaluation of characteristics of the test system.

A

Quality Control

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3
Q

Only part of the quality assurance

A

Quality control

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4
Q

With predetermined assay value; with same matrix as pxn sample

A

Control

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5
Q

Reference material used to calibrate the instrument or prepare standard curves for manual assays

A

Primary std

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6
Q

Reference material in which analyte conc. has been ascertained by reference to primary std.

A

Secondary std

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7
Q

Preserved human or surrogate cell suspension whose hematology parameters have been determined by multireference lab and monitored daily by the distributor

A

Callibrator

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8
Q

Nearness or closeness of measurement to the true/actual value

A

Accuracy

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9
Q

Closeness of results obtained from repeated analysis of the sample.

A

Precision

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10
Q

Comparing result from the analysis of the sample from the result of the previous sample of the same analyte

A

Delta checks

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11
Q

Extent to which the method is able to maintain accuracy and precision overtime

A

Reliability

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12
Q

Range of values

A

Reference values

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13
Q

Most popular and well know measure of central tendency

A

Mean

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14
Q

A measure of dispersion of values from the mean.

A

Standard Deviation

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15
Q

Helps discribe the normal curve

A

Standard deviation

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16
Q

Measure the distribution range

Measure of precision

A

Standard deviation

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17
Q

A percentile expression of the mean and an index of precision

A

Coefficient of variation

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18
Q

A measure of relative magnitude of variability

A

Coefficient of variation

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19
Q

Proportion of patients with a disease who have a positive test result

A

Diagnostic sensitivity

20
Q

Lowest amount of a substance that ca be detected accurately by a test method

A

Analytical sensitivity

21
Q

Proportion of patients who are identified correctly by the test as not having the disease

A

Diagnostic specificity

22
Q

How well a test method can detect a particular substance rather than similar ones

A

Analytical specificity

23
Q

Proportion of patients without a disease who have a positive result compared with all patients who a positive test result

A

Positive predictive value

24
Q

Proportions of patients w/o a disease who have a negative test result compared w/ all patients who have a negative test result

A

Negative predictive value

25
Q

Errors within the test system or method

Affects the accuracy of a test method

A

Systematic error

26
Q

Incorrect calibration procedures
Malfunctioning of components
Failure of some part of the testing process

A

Systematic error

27
Q

Type of systematic error that the magnitude of error remains constant throughout the range of the test measurement

A

Constant error

28
Q

Type of systematic error that the magnitude of error increases with the conc. of subs. being measures

A

Proportional error

29
Q

Mistakes that occur without predictions/regularity

A

Random error

30
Q

Instability of instrument
Change in temp
Operator variability
Affects boyh the accuracy but most is the precision of a test method

A

Random error

31
Q

Sources of error

A

Pre-analytical
Analytical
Post-analytical

32
Q

Misinterpreted physician test order

A

Pre-analytical

33
Q

Pxn midentification

A

Pre-analytical

34
Q

Errors in the actual testing of the specimens

A

Analytical

35
Q

Incorrect result entry

A

Post-analytical

36
Q

Incorrect pxn preparation

A

Pre-analytical

37
Q

Failure to notify the physician of critical result

A

Post-analytical

38
Q

Improper method of transport and handling

A

Pre-analytical

39
Q

Miscommunication of report to nursing unit/physician

A

Post-analytical

40
Q

Reports place in wrong patient chart

A

Post-analytical

41
Q

Incorrect sampling technique

A

Pre-analytical

42
Q

Improper collection container

A

Pre-analytical

43
Q

Analysis of control samples along with the patients samples and statistical evaluation of results to determine the acceptability of the analytical run

A

Internal qc

44
Q

Measure of precision overtime

A

Internal qc

45
Q

Indicated the mean and 1sd, 2sd, 3sd on both sides of the mean

A

Levey Jennings control chart

46
Q

Drift the values from one level of the control chart to another; either be sudden/gradual

A

Shift

47
Q

Continuous movement of values in one direction

A

Trend

48
Q

Samples will be used to the diff. lab by a reference lab. Proficiency testing programs

A

External QC

Hematology (6 decks)

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