Recombinant cytokines

Question 1

Identify the agent that is clinically used for:

Anemia (especially in renal failure)

Answer 1

• Agent: Epoetin alfa

Question 2

Identify the agent that is clinically used for:

Thrombocytopenia (2)

Answer 2

• Thrombopoietin
• Oprelvekin (IL-1)

Question 3

Identify the agent that is clinically used for:

Recovery from Bone marrow

Answer 3

• Filgrastim (G-CSF: granulocyte colony-stimulating factor)
• Sargramostim (GM-CSF: granulocyte-macrophage colony-stimulating factor)

Question 4

Identify the agent that is clinically used for:

renal cell carcinoma, metastatic melanoma

Answer 4

• Aldesleukin (IL-2)

Question 5

Identify the agent that is clinically used for:

Chronic hepatitis B & C, Kaposi sarcoma, hairy cell leukemia, condyloma acuminatum, renal cell carcinoma, malignant melanoma

Answer 5

• IFN-alpha

Question 6

Identify the agent that is clinically used for:

Multiple sclerosis

Answer 6

• IFN-beta

Question 7

Identify the agent that is clinically used for:

Chronic granulomatous disease

Answer 7

• IFN-gamma