Autoantibodies Flashcards

1
Q

Autoantibody (Id associated disorder)

Anti-ACh receptor

A

Associated disorder:

Mysthenia gravis

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2
Q

Autoantibody (Id associated disorder)

Anti-basement membrane

A

Associated disorder

Goodpasture syndrome

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3
Q

Autoantibody (Id associated disorder)

Anti-cardiolipin, lupus anticoagulant

A

Associated disorder

SLE, antiphospholipid syndrome

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4
Q

Autoantibody (Id associated disorder)

Anticentromere

A

Associated disorder

Limited scleroderma

(CREST syndrome)

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5
Q

Autoantibody (Id associated disorder)

Anti-desmoglein

A

Associated disorder

Pemphigus vulgaris

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6
Q

Autoantibody (Id associated disorder)

Anti-dsDNA, Anti-Smith

A

Assocatied Disorder

SLE

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7
Q

Autoantibody (Id associated disorder)

Anti-glutamate decarboxylase

A

Associated disorder

Type 1 diabetes mellitus

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8
Q

Autoantibody (Id associated disorder)

Anti-hemidesmosome

A

Associated disorder

Bullous pemphigoid

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9
Q

Autoantibody (Id associated disorder)

Anti-histone

A

Associated disorder

Drug-induced lupus

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10
Q

Autoantibody (Id associated disorder)

Anti-Jo-1, Anti-SRP, anti-Mi-2

A

Associated disorder

Polymyositis, dermatomyositis

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11
Q

Autoantibody (Id associated disorder)

Antimicrosomal, antithyroglobulin

A

Associated disorder

Hashimoto’s disease

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12
Q

Autoantibody (Id associated disorder)

Antimitochondrial

A

Associated disorder

1o biliary cirrhosis

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13
Q

Autoantibody (Id associated disorder)

Antinuclear antibodies

A

Assocaited disorder

SLE, nonspecific

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14
Q

Autoantibody (Id associated disorder)

Anti-Scl-70 (anti-DNA topoisomerase I)

A

Associated disorder

**Scleroderma (diffuse) **

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15
Q

Autoantibody (Id associated disorder)

Anti-smooth muscle

A

Associated disorder

Autoimmune hepatitis

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16
Q

Autoantibody (Id associated disorder)

Anti-SSA, Anti-SSB (anti-Ro, anti-La)

A

Associated disorder

Sjogren syndrome

17
Q

Autoantibody (Id associated disorder)

Anti-TSH receptor

A

Associated disorder

Graves disease

18
Q

Autoantibody (Id associated disorder)

c-ANCA (PR3-ANCA)

A

Associated disorder

Granulomatosis with polyangiitis (Wegener)

19
Q

Autoantibody (Id associated disorder)

IgA antiendomysial, IgA anti-tissue transglutaminase

A

Associated disorder

Celiac disease

20
Q

Autoantibody (Id associated disorder)

p-ANCA (MPO-ANCA)

A

Associated disorder

Microscopic polyangiitis, Churg-Strauss syndrome

21
Q

Autoantibody (Id associated disorder)

Rheumatoid factor (antibody, most commonly IgM, specific to IgG Fc region), anti-CCP

A

Associated Disorder

Rheumatoid arthritis