Reaction components Flashcards
SN2 products
Negatively charged atom, Nucleophile bonded to C, R, 2 H.
SN2
Nucleophile attacks alkyl halide, causing loss of leaving group
Good leaving groups
Conjugate bases of strong acids
E2
Base removes proton from beta position of alkyl halide, causing loss of leaving group
E2 products
Carbon double bonded to carbon, H bonded to base, atom with negative charge
Strong nucleophiles
I, Br, Cl, HS, RS, HO, RO, CN (All -ly charged)
Weak nucleophiles
H2O, ROH
SN1 mechanism
Loss of leaving group gives carbocation intermediate, nucleophile attacks positive charge
E1 products
Carbon with double bond and other single bonds, plus H bonded to +base
E1 mechanism
Loss of leaving group gives carbocation intermediate, base removes beta proton to be able to afford product.