RBC membrane Flashcards
1
Q
shape of rbc membrane
A
biconcave shape
2
Q
functions of rbc membrane
A
- Deformanility
- osmotic balance
- gas exchange
- support for antigens
always remember the DOGS!!
3
Q
intracellular ratio of Na+
A
1:12
4
Q
extracellular ratio of K+
A
25:1
5
Q
composition of rbc membrane
A
50% proteins
40% lipids
10% carbo
6
Q
what composition of rbc membrane produces sialic acid?
sialic acid also known as?
what is the purpose of sialic acid?
A
- integral protein (component A and glycophorin A)
- neuraminic aic (NeuNAc)
- gives rbc membrane a ZETA POTENTIAL
7
Q
enumerate the integral proteins
A
- glycophorin A, B, C
- component A
- anion-exchange channel protein
8
Q
enumerate the peripheral proteins
A
- spectrin (alpha and beta)
- protein 4.1
- actin
- dematin
- ankyrin
- tropomyosin
- tropomodulin
- adducin
9
Q
lipids external layers
A
- sphingomyelin
- phosphatidylcholine
10
Q
lipids internal layers
A
- phosphatidylinositol
- phosphatidylethanolamine
- phosphatidylserine
11
Q
composition of lipids
A
- external
- internal
- cholesterol in esterified form
12
Q
carbohydrates forms the ___ which protects the rbc from impact with other rbc
A
glycocalyx
13
Q
for calcium flow
A
Ca+ and ATPase
14
Q
Ca+ and ATPase are controlled by?
A
calmodulin
15
Q
distribution of lipids depends on what enzymes?
A
- flippases
- floppases
- scramblases
