MHC Flashcards

1
Q

MHC also known as

A

human leukocyte antigen

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2
Q

HLA is encoded from the gene found in?

A

short arm of chromosome 6

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3
Q

MHC can cause ___

A

immune response if transplanted

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4
Q

major function of MHC

A

binds to peptides within cell and transports it to plasma membrane

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5
Q

MHC bring antigen to cell surface for recognition by?

A

T cells

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6
Q

class I MHC has high levels on nucleated cells esp the?

A

lymphocytes

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7
Q

class I is low in the?

A

liver, muscle, sperm cell

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8
Q

class I is recognized by?

A

cytotoxic t cell (CD8+)

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9
Q

what are the class I MHC

A

HLA-A, HLA-B, HLA-C, HLA-E

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10
Q

class II are found on?

A
  • B cells
  • macrophage
  • dendritic cells (APC)
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11
Q

class II is recognized by what cells?

A

helper T cells (CD4+)

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12
Q

specific WBC that has something to do with MHC (HLA)

A

**T cells* ky sya mn ang ga recognized sa class I and II specifically 1 for CD8 2 for CD4

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13
Q

when T cells are activated by antigen, they start to secrete __

A

cytokines

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14
Q

enumerate the leukocytes that function as APC

A
  • macrophage
  • neutrophils
  • some B cells
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