MHC Flashcards
MHC also known as
human leukocyte antigen
HLA is encoded from the gene found in?
short arm of chromosome 6
MHC can cause ___
immune response if transplanted
major function of MHC
binds to peptides within cell and transports it to plasma membrane
MHC bring antigen to cell surface for recognition by?
T cells
class I MHC has high levels on nucleated cells esp the?
lymphocytes
class I is low in the?
liver, muscle, sperm cell
class I is recognized by?
cytotoxic t cell (CD8+)
what are the class I MHC
HLA-A, HLA-B, HLA-C, HLA-E
class II are found on?
- B cells
- macrophage
- dendritic cells (APC)
class II is recognized by what cells?
helper T cells (CD4+)
specific WBC that has something to do with MHC (HLA)
**T cells* ky sya mn ang ga recognized sa class I and II specifically 1 for CD8 2 for CD4
when T cells are activated by antigen, they start to secrete __
cytokines
enumerate the leukocytes that function as APC
- macrophage
- neutrophils
- some B cells