Complements

Question 1

effects of complement (MOLIC)

Answer 1

• chemotaxis
• lysis of cells
• mediators
• opsonization
• increase vascular permeability

Question 2

function of complement

Answer 2

completes the antigen-antibody complex

Question 3

complement are ___ proteins that are most synthesized in the ___

Answer 3

• non-specific proteins
• synthesized in the liver

Question 4

3 known pathways of complement

Answer 4

• classical
• alternative
• lectin

Question 5

3 pathways converge at the activation of the component __?

Answer 5

C3

Question 6

antibody involved in the activation of classical pathway

Answer 6

Ig1, Ig3, IgM

Question 7

an enzyme involved in the activation of lectin pathway

Answer 7

mannan-binding lectin serine protease

Question 8

serum proteins of the alternative pathway

Answer 8

• factor B
• factor D
• properdin
• initiating factor

Question 9

polymerization of these complement component enhances the MAC formation

Answer 9

C8 and C9

Question 10

complement component that has the lowest concentration of all complement proteins which is produced by adipose

Answer 10

C3 proactivator convertase

Question 11

final step of complement activation

Answer 11

MAC (membrane attack complex) formation

Question 12

complements known as the MAC in the classical pathway

Answer 12

C5B, C6, C7, C8, C9

Question 13

recognition unit in the classical pathway

Answer 13

C1q

Question 14

what MHC class encodes complement components

Answer 14

class II