RBC Anomalies (Page 245-246) Flashcards
Abnormal vairation in RBC volume or diameter (SIZE)
Anisocytosis
What is the normal size of an RBC?
6-8 um in diameter
What is the normal MCV?
80-100 fl
These are large RBCs with >8um in diameter and MCV >100fl
Macrocytes
What are the commonly associated disease states in anisocytosis?
Hemolytic, megaloblastic, irondeficiency anemia
These are large oval RBCs
Oval Macrocyte
These are small RBCs; diameter <80fl
Microcyte
Abnormal variation in RBC shape
Poikilocytosis
These are small, round, dense RBC with no central pallor
Spherocyte
These are elliptical (Cigar shaped), oval (Egg shaped) RBC
Elliptocyte, Ovalocyte
RBC with a slitlike are of central pallor
Stomatocyte
These are thin, dense, elongated RBC pointed at each end; may be curved
Sickle cell
Hexagonal crystal of dense hemoglobin formed within the RBC membrane
Hb C Crystal
Fingerlike or quartzlike crystal of dense hemoglobin protruding from the RBC membrane
Hb SC Crystal
RBC with hemoglobin concentrated in the center and around the periphery resembling a target
Target cell
Codocyte
Fragmented RBC due to rupture in the peripheral circulation
Schistocyte
Schizocyte
RBC Fragment in a shape of a helmet
Helmet cell
Keratocyte
RBC with membrane folded over
Folded cell
Small dense RBC with few irregularly spaced projections of varying length
Acanthocyte
Thorn/Spurr Cell
RBC with blunt or pointed, short projections that are usually evenly spaced over the surface of the cell; present in all fields of blood film but in variable numbers per field
Burr Cell
Echinocyte
RBC with a single pointed extension resembling a teardrop or pear
Teardrop cell
Dacrocyte
Other name for Teardrop cell
Dacrocyte
Other name for Burr cell
Echinocyte
Other name for Spurr cell
Acanthocyte
