Ch. 14 - Erythrocyte Sedimentation Rate Flashcards
Which among the following is ESR found to be normal? First 24 hours of acute appendicitis Osteoarthritis Rheumatic fever Rheumatoid arthritis Pyogenic arthritis Early stage of acute pelvic inflammatory disease Ruptured ectopic pregnancy
Osteoarthritis
First 24 hours of acute appendicitis
This is commonly used as a general screening test and it is useful for monitoring the course of an existing inflammatory diseaseor for differentiating between similar diseases.
Erythrocyte Sedimentation Rate (ESR)
Which among the following is ESR found to be elevated? First 24 hours of acute appendicitis Osteoarthritis Rheumatic fever Rheumatoid arthritis Pyogenic arthritis Early stage of acute pelvic inflammatory disease Ruptured ectopic pregnancy
Rheumatic fever Rheumatoid arthritis Pyogenic arthritis Early stage of acute pelvic inflammatory disease Ruptured ectopic pregnancy
This is the distance in millimeters that the RBCs fall in 1 hr.
ESR
Enumerate factors that affect the ESR
Erythrocytes
Plasma
Mechanical and technical factors
The repulsive forces of the negatively charged surfaces of erythrocytes are partially or totally counteracted if there are increased quantities of positively charged plasm proteins; the erythrocytes settle more rapidly as a result of the formation of RBC aggregates or rouleaux. Give examples of macromolecules that can produce this reaction.
Fibrinogen
Beta-globulins
Pathologic immunoglobulins
(T/F) ESR is inversely proportional to the RBC mass and directly proportional to plasma viscosity.
F
The most commonly used method for ESR measurement
Modified Westergren ESR
One advantage of this method for measuring ESR is that is uses a taller column height that allows the detection of highly elevated ESR.
Modified Westergren ESR
It is the method of ESR measurement recommended by the International Council for Standardization in Hematology and the Clinical and Laboratory Standard Institute.
Modified Westergren ESR
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What type of blood should be used in the Modified Westergren ESR?
Blood collected in EDTA and dilute at four parts blood to one part 3.8% sodium citrate or 0.85% sodium chloride
Blood collected directly into special sedimentation test tube containing sodium citrate
The Blood collected in EDTA is diluted at four parts blood to one part _____ or _____.
- 8% sodium citrate
0. 85% sodium chloride
Aside from blood collected from an EDTA tube, what type of blood an be used for Modified Westergren ESR?
Blood collected directly into special sedimentation test tube containing sodium citrate
The column used in Modified Westergren ESR has a ___ mm height and ___ internal diameter or more.
200
2.55
In Modified Westergren ESR, how long will the column be allowed to stand undisturbed?
60 mins
This was the sample used when the Wintrobe ESR was first introduced.
Oxalate-anticoagulated whole blood .
This was the height of the column used when the Wintrobe ESR was first introduced.
100mm
This is the present sample used in the Wintrobe ESR.
EDTA treated whole blood
Citrated whole blood
In Wintrobe ESR, the column used at present is (longer/shorter) than the column used when it was first introduced.
Shorter
In Wintrobe ESR, the shorter column height used allows an increased _____ in detecting mildly elevated ESRs.
Sensitivity
In Wintrobe ESR, what is the minimum amount of blood, collected in EDTA, needed?
2mL
What is the reference range for the ESR of males 0-50 years of age?
0-15 mm
What is the reference range for the ESR of males >50 years of age?
0-20 mm
