RBC Abnormalities: Inclusions

Question 1

Nuclear fragments (DNA)

Seen in:
Feulgen Reactions
Megaloblastic Anemia

Answer 1

Howell-Jowell Bodies

Question 2

Deep blue to purple granules
Aggregation of ribosome

Answer 2

Basophilic stipplings

Question 3

Seen in Lead and Arsenic Poisoning
Pyrimidine-5-deficiency

Answer 3

Basophilic Stippling

Question 4

Stippling most commonly seen in INCREASED POLYCHTOMATOPHILIA and therefore increased RBC production

Answer 4

Fine stippling

Question 5

Stippling seen in LEAD POISONING and impaired Hgb synthesis, megaloblastic anemia

Answer 5

Coarse stippling

Question 6

Thin ring structure
mitotic spindle

Seen in DYSERYTHROPOIESIS

Answer 6

Cabot rings

Question 7

Consist of Denatured Globin
Pitted out by the spleen

Answer 7

Heinz Bodies

Question 8

Seen in G6PD Deficiency
Unstable Hgb (Zurich, Koln)
Oxidant Drugs
Splenectomized patients

Answer 8

Heinz Bodies

Question 9

Multiple Heinz bodies may give cell appearance of

Answer 9

PITTED GOLF BALL

Question 10

Result of Splenic spitting of Heinz Bodies

Answer 10

Bite and Blister Cell

Question 11

Seen in patient with PRECIPITATE OF B-chains of Hgb stained with Brillian Cresyl Blue

Answer 11

Hgb H Bodies

Question 12

Seen in alpha thalassemia patient with Moderate Hemolytic Anemia

Answer 12

Hgb H disease

Question 13

Gold bar or Washington monument
Homozygous C Disease

Answer 13

Hemoglobin C Crystals

Question 14

Hb AC Trait

a. with crystals
b. w/o crystals

Answer 14

w/o crystals

Question 15

Crystal with Glove or Pistol appearance
Washington monument

Answer 15

Hemoglobin SC crystals

Question 16

Nucleated RBC with non-heme iron particles

Excess iron overload due to defective heme synthesis

Answer 16

Sideroblast

Question 17

Non-nucleated cell; Excessive iron overload in mitochondria

Answer 17

Siderocyte

Question 18

Plasmodium spp. transmitted by

Answer 18

Female Anopheles mosquito

Question 19

P.vivax

Answer 19

Shuffner’s dots

Question 20

P.malariae

Answer 20

Ziemann stippling

Question 21

P. falciparum

Answer 21

Maurer’s dot

Question 22

P. ovale

Answer 22

Shuffner’s dot
James dots

Question 23

Most common cause of babesiosis in US

Answer 23

B. Microti

Question 24

Babesiosis is also called _______ it was found on ____________

Answer 24

Nantucket Fever
Nantucket Island

Question 25

Tetrads in RBC; MALTESE CROSS

Answer 25

Babesia spp.

Question 26

SUPRAVITAL STAINING:

Reticulum

Answer 26

New Methylene Blue

Question 27

SUPRAVITAL STAINING:

Hb H Inclusions

Answer 27

Brilliant Cresyl Blue

Question 28

SUPRAVITAL STAINING:

HeinZ Bodies

Answer 28

Crystal Violet

CryZtal Violet

Question 29

Best Vital Dye

Answer 29

Neutral Red

Question 30

Stain for Mitochondria

Answer 30

Janus Green