RBC Abnormalities: Hgb Content Flashcards
variation of the color of erythrocytes caused by unequal Hgb concentration
Anisochromia
Central pallor does not exceed 1/3 RBC diameter
MCHC = 31-36%
Normochromic RBC
Normochromic RBC are seen in patients with
AHA
Acute Blood Loss
Hemolytic Anemia
Aplastic Anemia
Central pallor >1/3 red cells
MCHC <31%
Hypochromic RBC
Hgb Characteristics of patient with:
Anemia of Chronic Inflammation
Thalassemia
IDA
Sideroblastic Anemia
Hypochromic
Hypochromia Grading
- Central pallor is 1/2 of cell diameter
- Central pallor is 2/3 of cell diameter
- Central pallor is 3 quarters
- thin rim of Hgb
1+
2+
3+
4+
No central pallor
MCHC >36%
Hyperchromic
Condition by which Hyperchromic RBC are seen
Hereditary Spherocytosis
Hyperchromic RBC has a shape of
Spherocytes (decrease in spectrin)
Blue-gray tint to red cells
Young RBC contains residual RNA
Polychromatic RBC
Reticulocytes are stained with
Brilliant Cresyl Blue
Polychromatic RBC are seen in patient with
Hemolysis
Hemorrhage
Polychromatic Grading
Slight
1+
2+
3+
4+
Slight 1%
1+ 3%
2+ 5%
3+ 10%
4+ >11%
The presence of Hypochromic and Normochromic in same film
Dimorphic anemia
Seen in patients with:
- Sideroblastic anemia
- weeks after iron therapy
- Hypochromic anemia after transfusion w/ normal cells
Dimorphic anemia