Rate Limiting Enzymes Flashcards

1
Q

Glycolysis

A

Phosphofructokinase-I

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2
Q

Gluconeogenesis

A

Fructose-1,6-biphosphatase

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3
Q

Glycogenesis

A

Glycogen synthase

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4
Q

TCA cycle

A

Isocitrate dehydrogenase

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5
Q

Glycogenolysis

A

Glycogen phosphorylase

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6
Q

HMP shunt

A

Glucose-6-phosphate dehydrogenase

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7
Q

De Novo pyrimidine synthesis

A

Carbamoyl phosphate synthetase II

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8
Q

De Novo purine synthesis

A

GLutamine-phosphoribosylpyrophospate

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9
Q

Urea cycle

A

Carbamoyl phosphate synthetase I

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10
Q

Fatty acid synthesis

A

Acetyl CoA carboxylase

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11
Q

Fatty acid oxidation

A

Carnitine acyltransferase I

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12
Q

Ketogenesis

A

HMG CoA synthase

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13
Q

Cholesterol synthesis

A

HMG CoA reductase

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14
Q

Positive regulators of glycolysis

A

AMP, fructose-2,6-biphosphate

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15
Q

Negative regulators of glycolysis

A

ATP, citrate

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16
Q

Negative regulators of gluconeogenesis

A

AMP, fructose-2,6-biphosphate

17
Q

Positive regulators of TCA cycle

A

ADP

18
Q

Negative regulators of TCA cycle

A

ATP, NADPH

19
Q

Positive regulators of glycogenesis

A

Glucose-6-phosphate, insulin, cortisol

20
Q

Negative regulators of glycogenesis

A

Epinephrine, Glucagon

21
Q

Positive regulators of glycogenolysis

A

Epinephrine, Glucagon, AMP

22
Q

Negative regulators of glycogenolysis

A

Glucose-6-phosphate, insulin, ATP

23
Q

Positive regulators of HMP shunt

A

NADP

24
Q

Negative regulators of HMP shunt

A

NADPH

25
Q

Positive regulators of Cholesterol synthesis

A

Insulin, Thyroxine

26
Q

Negative regulators of Cholesterol synthesis

A

Glucagon, Cholesterol

27
Q

Positive regulators of Urea cycle

A

N-acetylglutamate

28
Q

Negative regulators of Fatty acid oxidation

A

Malonyl-CoA