Nucleotides

Question 1

(2) nucleotides with Purine bases

Answer 1

Adenine
Guanine

(Pure As Gold)

Question 2

(3) nucleotides with Pyrimidine bases

Answer 2

Uracil
Thymine
Cytosine

(CUT the Py)

Question 3

Rate limiting enzyme of Purine synthesis

Answer 3

PRPP glutamyl amidotransferase

Question 4

Rate limiting enzyme of Pyrimidine Synthesis

Answer 4

Carbamoyl phosphate synthethase II

Question 5

Parent Molecule of Purine synthesis

Answer 5

Inosine Monophosphate (IMP)

Question 6

Parent Molecule of Pyrimidine synthesis

Answer 6

Orotidine Monophosphate

Question 7

Drug that inhibit Xanthine oxidase

Answer 7

Allopurinol

Question 8

Drug that inhibit dhydropteroate synthase

Answer 8

Sulfonamide

Question 9

Drug that inhibit thymidylate synthase

Answer 9

5-Fluorouracil

Question 10

Reversible inhibitor of IMP dehydrogenase

Answer 10

Mycophenolate

Question 11

Drug that inhibit dhydropteroate reductase

Answer 11

Trimethrophrim

Methotrexate

Question 12

Enzyme deficient in SCID

Answer 12

Adenosine deaminase

Question 13

Enzyme deficient in von Gierke disease

Answer 13

Glucose-6-phosphatase

Question 14

Enzyme deficient in Beta Hydroxybutyricaciduria

Answer 14

Dihydropyrimidine dehydrogenase

Question 15

in DNA, Adenine is always paired with

Answer 15

Thymine

Question 16

in DNA, Guanine is always paired with

Answer 16

Cytosine

Question 17

Most common structural form of DNA

Answer 17

B- DNA

Question 18

RNA pyrimidine components

Answer 18

Cytosine and Uracil

Question 19

DNA pyrimidine components

Answer 19

Cytosine and Thymine

Question 20

Copies genetic information from DNA and serves as template for protein synthesis

Answer 20

mRNA

Question 21

Contribute to the formation and function of ribosomes which acts as site for protein synthesis

Answer 21

rRNA

Question 22

Adapter molecules that translate the nucleotide sequence of mRNA

Answer 22

tRNA

Question 23

Contains the anticodon

Answer 23

tRNA

Question 24

involved in rNA and mRNA splicing

Answer 24

snRNA

Question 25

During what phase of cell cycle DNA replication occurs

Answer 25

S phase

Question 26

Y shaped region along DNA template where leading and lagging strands are synthesized

Answer 26

Replication fork

Question 27

Unwinds DNA template at the replication fork

Answer 27

Helicase

Question 28

Prevents strands from reannealing

Answer 28

ss DNA binding proteins

Question 29

Relieves torsions or DNA supercoils

Answer 29

Topoisomerases

Question 30

Synthesizes short segments of complementary RNA primers

Answer 30

Primases

Question 31

Elongates DNA strand by adding new deoxyribonucleotides

Answer 31

DNA polymerase III

Question 32

Degrades RNA primer

Answer 32

DNA polymerase I

Question 33

Catalyzes the formation of phosphodiester bonds | Joins okazaki fragments

Answer 33

DNA ligase

Question 34

Synthesis of RNA using DNA as template

Answer 34

Transcription

Question 35

Synthesis of proteins in ribosomes using mRNA as template

Answer 35

Translation

Question 36

mRNA start codon

Answer 36

AUG (rarely GUG)

Question 37

mRNA stop codons

Answer 37

UGA UAA UAG

Question 38

Characteristic of genetic code where multiple codons may code for the same AA

Answer 38

Degenerate

Question 39

Characteristic of genetic code where a specific codon always code for the same AA

Answer 39

Unambiguous

Question 40

Characteristic of genetic code where codons are read in acontinuing sequence

Answer 40

Nonoverlapping

Question 41

Characteristic of genetic code where it is conserved that only slight differences occur in manner which the code is translated

Answer 41

Universal

Question 42

Drug that inhibit transcripption by binding to Beta subunit of bacterial DNA dependent RNA polymerase

Answer 42

Rifampicin

Question 43

Drug that inhibit transcription by binding to DNA template and interferes with the movement of RNA polymerase

Answer 43

Dactinomycin

Question 44

Drug that inhibit protein synthesis by binding to 30s subunit

Answer 44

Steptomycin | Aminoglycosides

Question 45

Drug that inhibit protein synthesis by preventing aminoacyl-tRNA binding at the A site

Answer 45

Tetracycline

Question 46

Drug that inhibit protein synthesis by inhibiting peptidyltransferases

Answer 46

Chloramphenicol

Question 47

Drug that inhibit protein synthesis by binding to 50s subunit and inhibits translocation

Answer 47

Clindamycin | Macrolides