Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Topnotch Biochemistry (Sept 2017) > Nucleotides > Flashcards

Nucleotides Flashcards

1
Q

(2) nucleotides with Purine bases

A

Adenine
Guanine

(Pure As Gold)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

(3) nucleotides with Pyrimidine bases

A

Uracil
Thymine
Cytosine

(CUT the Py)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Rate limiting enzyme of Purine synthesis

A

PRPP glutamyl amidotransferase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Rate limiting enzyme of Pyrimidine Synthesis

A

Carbamoyl phosphate synthethase II

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Parent Molecule of Purine synthesis

A

Inosine Monophosphate (IMP)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Parent Molecule of Pyrimidine synthesis

A

Orotidine Monophosphate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Drug that inhibit Xanthine oxidase

A

Allopurinol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Drug that inhibit dhydropteroate synthase

A

Sulfonamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Drug that inhibit thymidylate synthase

A

5-Fluorouracil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Reversible inhibitor of IMP dehydrogenase

A

Mycophenolate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Drug that inhibit dhydropteroate reductase

A

Trimethrophrim

Methotrexate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Enzyme deficient in SCID

A

Adenosine deaminase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Enzyme deficient in von Gierke disease

A

Glucose-6-phosphatase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Enzyme deficient in Beta Hydroxybutyricaciduria

A

Dihydropyrimidine dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

in DNA, Adenine is always paired with

A

Thymine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

in DNA, Guanine is always paired with

A

Cytosine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Most common structural form of DNA

A

B- DNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

RNA pyrimidine components

A

Cytosine and Uracil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

DNA pyrimidine components

A

Cytosine and Thymine

20
Q

Copies genetic information from DNA and serves as template for protein synthesis

A

mRNA

21
Q

Contribute to the formation and function of ribosomes which acts as site for protein synthesis

A

rRNA

22
Q

Adapter molecules that translate the nucleotide sequence of mRNA

A

tRNA

23
Q

Contains the anticodon

A

tRNA

24
Q

involved in rNA and mRNA splicing

A

snRNA

25
Q

During what phase of cell cycle DNA replication occurs

A

S phase

26
Q

Y shaped region along DNA template where leading and lagging strands are synthesized

A

Replication fork

27
Q

Unwinds DNA template at the replication fork

A

Helicase

28
Q

Prevents strands from reannealing

A

ss DNA binding proteins

29
Q

Relieves torsions or DNA supercoils

A

Topoisomerases

30
Q

Synthesizes short segments of complementary RNA primers

A

Primases

31
Q

Elongates DNA strand by adding new deoxyribonucleotides

A

DNA polymerase III

32
Q

Degrades RNA primer

A

DNA polymerase I

33
Q

Catalyzes the formation of phosphodiester bonds | Joins okazaki fragments

A

DNA ligase

34
Q

Synthesis of RNA using DNA as template

A

Transcription

35
Q

Synthesis of proteins in ribosomes using mRNA as template

A

Translation

36
Q

mRNA start codon

A

AUG (rarely GUG)

37
Q

mRNA stop codons

A

UGA
UAA
UAG

38
Q

Characteristic of genetic code where multiple codons may code for the same AA

A

Degenerate

39
Q

Characteristic of genetic code where a specific codon always code for the same AA

A

Unambiguous

40
Q

Characteristic of genetic code where codons are read in acontinuing sequence

A

Nonoverlapping

41
Q

Characteristic of genetic code where it is conserved that only slight differences occur in manner which the code is translated

A

Universal

42
Q

Drug that inhibit transcripption by binding to Beta subunit of bacterial DNA dependent RNA polymerase

A

Rifampicin

43
Q

Drug that inhibit transcription by binding to DNA template and interferes with the movement of RNA polymerase

A

Dactinomycin

44
Q

Drug that inhibit protein synthesis by binding to 30s subunit

A

Steptomycin

Aminoglycosides

45
Q

Drug that inhibit protein synthesis by preventing aminoacyl-tRNA binding at the A site

A

Tetracycline

46
Q

Drug that inhibit protein synthesis by inhibiting peptidyltransferases

A

Chloramphenicol

47
Q

Drug that inhibit protein synthesis by binding to 50s subunit and inhibits translocation

A

Clindamycin

Macrolides

Topnotch Biochemistry (Sept 2017) (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions