Rate-Determining Enzymes of metabolic processes Flashcards
1
Q
Glycolysis?
A
Phosphofructokinase-1 (PFK-1)
+AMP and fructose 2,6-bisphosphate
2
Q
Gluconeogenesis?
A
Fructose-1,6-bisphosphatase
+ATP and Acetyl-CoA
3
Q
TCA cycle?
A
Isocitrate dehydrogenase
+ADP
4
Q
Glycogenesis?
A
Glycogen synthase
+glucose 6-phosphate
5
Q
Glycogenolysis
A
Glycogen phosphorylase
6
Q
HMP shunt
A
G6PD
7
Q
New pyrimidine synthesis?
A
Carbamoyl phosphate synthetase II
8
Q
New purine synthesis?
A
PRPP amidotransferase
9
Q
Urea cycle?
A
Carbamoyl phosphate synthetase I
+ cofactor: N-acetylglutamate
10
Q
Fatty acid synthesis?
A
Acetyl-CoA carboxylase (ACC)
11
Q
Fatty acid oxidation?
A
Carnitine acyltransferase I
12
Q
Ketogenesis?
A
HMG-CoA synthase
13
Q
Cholesterol synthesis
A
HMG-CoA reductase
stimulated by thyroxine
