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UWorld Review Incorrects > Rapid Review Relevant Treatments > Flashcards

Rapid Review Relevant Treatments Flashcards

1
Q

ethylene glycol/methanol intoxication

A

fomepizole (alcohol dehydrogenase inhibitor)

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2
Q

chronic hep B or C

A

IFNa (HBV & HCV)
ribavirin, simeprevir, sofosbuvir (HCV)

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3
Q

s bovis

A

penicillin prophylaxis
eval colon cancer if linked to endocarditis

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4
Q

C botulism

A

human botulinim immunoglobulin

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5
Q

C tentani

A

antitoxin and wound debridement

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6
Q

hae infl b

A

amoxicillin + clavuclanic acid (mucosal infections)
ceftriaxone (meningitis)
rifampin (prophylaxis)

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7
Q

N gonorrhea

A

ceftriaxone (+ azithromycin/doxycycline to cover concurrent C trachomatis)

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8
Q

N meningitis

A

pencillin/ceftriaxone
rifampin/ciprofloxacin/ceftriaxone (prophylactic)

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9
Q

legionella

A

macrolides (azithromycin or fluoroquinolones)

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10
Q

psedomonas

A

piperacillin-tazobactam, cephalsporins, monobactams, fluroquinolones, carbapenems

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11
Q

treponema pallidum

A

penicillin G

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12
Q

chylamidia trachomatis

A

azithromycin/doxycycline (+ ceftriaxone for coinfection w/ gonorrhea)
oral erythromycin to treat chlamydial conjunctivitis in infants

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13
Q

candida albicans

A

topical azoles (vaginitis)
nystatin, fluconazole, caspofungin (oral)
fluconazole, caspofungin, amph B (esophageal/systemic)

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14
Q

cryptococcus neoformans

A

induction w/ amph B and flucytosine, maintance w/ fluconazole (in AIDS+)

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15
Q

sporothrix schenckii

A

itraconazole, oral potassium iodide

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16
Q

pneumocystis jirovecii

A

TMP-SMX (prophylasis + treatment in immuno suppressed, CD4<200)

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17
Q

toxoplasma gondii

A

sulfadizaine + pyrumethamine

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18
Q

malaria

A

chloroquine, mefloqunine, atovaqunone/proguanil (blood schizont)
primiquine (liver hpnozoite)

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19
Q

trichamonas vaginalis

A

metronidazole (patient and partners)

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20
Q

strept pyogenes

A

penicillin prophylaxis

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21
Q

strept pneumo

A

penicillin/cephlosporin (systemic infection, pneumo)
vancomycin (meningitis)

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22
Q

staph aureus

A

MSSA: nafillin, oxacillin, dicloxacillin (antistaph penicillins)
MRSA: vancomycin, daptomycin, linezolid, ceftroline

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23
Q

enterococci

A

vancomycin, aminopenicillins/cepf
VRE: daptomycin, linezoloid, tigecycline, streptogramins

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24
Q

rickettsia rickettsii

A

doxycycline, chloramphenicol

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25
Q

mycobacterium TB

A

Rifampin- red/orange body fluids
Isoniazid- vit B6 def, hepatotoxic
Pyrazinamide- gout
Ethambutol- optic neuropathy (red/green color blind)

**2nd line streptomycin- tinnitus/vertigo

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26
Q

UTI prophyalaxis

A

TMP-SMX

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27
Q

influenxa

A

oseltamivir
zanamivir

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28
Q

CMV

A

ganciclovir, foscarnet, cidofovir

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29
Q

PDA

A

close> indomethacin
open> PGE

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30
Q

stable angina

A

sublingual nitroglycerin

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31
Q

hypercholesterolemia

A

stain (1st line)

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32
Q

hypertriglycerides

A

fibrate

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33
Q

arrhythmia in damaged cardiac tissue

A

Class 1B anti-arryhtmic (lidocaine, mexiletine)

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34
Q

prolactinoma

A

cabergoline/bromocriptine (D agonists)

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35
Q

diabetes inspidius

A

central>desmopressin
nephrogenic> HCZT, indomethacin, amiloride

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36
Q

SIADH

A

fluid restriction, IV hypertonic saline, conivaptan/tolvaptan, demeclocycline

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37
Q

DKA/HHS

A

fluids, insulin, K+

38
Q

pheochromo

A

alpha-antagonists (phenoxybenzamine)

39
Q

carcinoid syndrome

A

octreotide, teltristat

40
Q

DM1

A

insulin replacement + low card diet

41
Q

DM2

A

oral hypoglycemics, diet interventions, insulin (if refractory from cell exhaustion)

42
Q

Chrons

A

corticosteroids, infliximab, azathioprine

43
Q

ulcerative colitis

A

5-ASA preparations (mesalamine)
6-mercaptopurine
infliximab
colectomy

44
Q

sickle cell anemia

A

hydroxyurea (inc fetal Hb)

45
Q

chronic myelogenous leukemia (CML)

A

BCR-ABL tyrosine kinase inhibitors (imatinib)

46
Q

acute promyelocytic leukemia (M3)

A

all-trans retinoic acid, arsenic trioxide

47
Q

1 anti-coagulation in pregnancy

A

low molecular weight heparin

48
Q

immediate anti-coagulation

A

heparin

49
Q

heparin reversal

A

protamine sulfate

50
Q

warfarin reversal

A

vit K (slow response)
FFP/prothrombin complex concentrate (fast)

51
Q

dabigatran reversal

A

idarucizumab

52
Q

direct factor Xa inhibitor reversal

A

andexanet alfa

53
Q

HER2+ breast cancer

A

trastuzamab

54
Q

hemorrhagic cystitis from cyclophasphamide/ifosfamide

A

mesna

55
Q

nephrotoxicity from platinum compounds

A

amifostine

56
Q

cardiotoxicity from anthracyclines

A

dexrazoane

57
Q

myelosuppresion from methotrexate

A

leucovorin

58
Q

osteoporosis

A

Ca/Vit D supplementation (prophylaxis)
bisphosphonates, PTH analogs, SERMs, calcitonin, densumab (tx)

59
Q

osteomalacia/rickets

A

Vit D supplementation

60
Q

chronic gout

A

xanthine oxidase inhibitors (allopurinol, febuxostat)
pegloticase
probenecid

**rasburicase for hyperuricemia in malignancy

61
Q

acute gout attack

A

NSAIDs, colchicine, glucocorticoids

62
Q

buerger disease

A

smoking cessation

63
Q

Kawasaki disease

A

IVIG, aspirin

64
Q

temporal arteritisi

A

high dose glucocorticoids

65
Q

granulomastis w/ polyanggiitis

A

cyclophosphamide, glucocorticoids

66
Q

neural tube defect prevention

A

folaic acid prenatal vitamins

67
Q

migraine

A

abortive tx: sumatriptan, NSAIDs
prophyalxis: propanolol, topiramate, anti-CGRP antibodies, amitrptyline

68
Q

MS

A

disease modifying tx: B-interferon, glatiramer, natalizumab
acute flare: IV steroids

69
Q

tonic-clonic seizures

A

levetiracetam, phenytonin, valproate, carbamazepine

70
Q

abscence seizures

A

ethosuximide

71
Q

tic doulourex (trigeminal neuralgia)

A

carbamazepine

72
Q

maligant hyperthermia (s/p anesthesia)

A

dantrolene

73
Q

anorexia

A

nutrition, psychotx, SSRIs

74
Q

bulemia nervosa

A

nutrition, rehabilitation, psychtx, SSRIs

75
Q

alcohol use disorder

A

disulfiram, acamprostate, naltrexone, supportive care

76
Q

ADHD

A

amphetamines, behavior tx, atomoxetine (non-stimulant)

77
Q

alcohol withdrawal

A

long-acting benzos

78
Q

bipolar disorder

A

mood stabilizers (lithium, valproic acid, carb)
atypical antipsychotics

79
Q

depression

A

SSRIs (1st line)

80
Q

GAD

A

SSRIs, SNRIs (1st line), buspirone (2nd line)

81
Q

schizophrenia

A

atypical antipsychotics

82
Q

hyperaldosteronism

A

spironolactone

83
Q

BPH

A

a1 antagonists: terazosin, tamsulosin (selective)
5a reductase inhibitors
PDE-5 inhibitors
TURP

84
Q

infertility

A

leuprolide, GnRH (pulsatile), clomiphene

85
Q

breast cancer in postmenopausal F

A

aromatase inhibitor (anastrozole)

86
Q

ER/PR+ breast cancer

A

tamoxifen

87
Q

uterine fibroids

A

leuprolide, GnRH (continuous)

88
Q

medical abortion

A

mifepristone

89
Q

prostate adenocarcinoma

A

flutamide, GnRH (continuous), degarelix, ketoconazole

90
Q

erectile dysfunction

A

sildenafil

91
Q

pulmonary arterial HTN (idopathic)

A

sildenafil, bosentan, epoprostenol, iloprost

UWorld Review Incorrects (12 decks)

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