Random Qs

Question 1

side effects diazoxide

Answer 1

used to treat refractory hypoglycemia due to hyperinsulinism in neonates

• fluid retension
• nausea
• blood dyscrasias
• hypertrichosis

Question 2

Side effects metformin

Answer 2

GI symptoms- diarrhoea, nausea, heartburn, abdo pain, bloating
aids in weight loss

Question 3

which antibiotic does vancomycin most closely resemble

Answer 3

teicoplanin

Question 4

action of botulinum neurotoxin

Answer 4

inhibits the release of acetylcholine into the synaptic junction

Question 5

insulin MOA

Answer 5

binds to transmembrane receptor - enzyme coupled

Question 6

MOA sildenafil

Answer 6

Used for PPHN
Phosphodiesterase inhibitor (inihibits PDE type 5) which is found in the smooth muscle of pulmonary vasculature, where it is responsible for the degredation of cGMP
Sildenafil increases cGMP within pulmonary smooth muscles cells leading to smooth muscle relaxation

Question 7

MoA TAmiflu (oseltamivir)

Answer 7

inhibit viral neuraminidase from allowing exit from the cell

Question 8

how do glucocorticoids lead to osteoporosis

Answer 8

suppress formation of new bone by inhibiting osteoblasts
osteoclast mediated resoprption remains the same
therefore there is net loss of bone

Question 9

MoA of bisphosphonates

Answer 9

inhibit osteoclasts , thus inhibit bone resorption

Question 10

MoA N acetylcysteine

Answer 10

reverses the acetaminophen-induced depletion of glutathione by increasing glutathione synthesis
provides cysteine for glytothione synthesis

Question 11

MOA ondansetron

Answer 11

serotonin 5-HT3 receptor antagonists.
It works by blocking the action of serotonin