Genetics

Question 1

Haploinsufficiency

Answer 1

when one copy of a gene is not enough to preserve normal function, ie two
Copies are required

Question 2

Dominant negative

Answer 2

a mutation who’s gene product adversely affects the normal
Wild type gene product within the same cell

Question 3

what direction is a new DNA/RNA strand created

Answer 3

5-3’
Neucleotides always added to the 3’ end

Question 4

DNA replication

Answer 4

RNA primer needed to start replication
DNA polymerase ade nucleotides to 3’ end
Helicase unwinds
Topoisomerase prevents supercoiling

Question 5

What inheritnace patter in androgen insensitivity syndrome

Answer 5

X linked recessive
all males
may have ambigious genitalia/look like females
then look more masculine at puberty