Random Haem

Question 1

What drugs cause drug induced thrombocytopenia?

Answer 1

Mainly antibiotics,
Furosemide
Ranitidine

Question 2

What’s the main constituent of cryoprecipitate?

Answer 2

Factor VIII

Fibrinogen

Question 3

What is an aplasic crisis? What do the blood results show?

Answer 3

Marrow failure, cannot produce RBCs. Often caused by parvovirus B19

Low hb, low reticulocytes

Question 4

Causes of gingival hyperplasia?

Answer 4

Phenytoin
Ciclosporin
Calcium channel blockers (nifedipine)

Acute myeloid leukaemia

Question 5

What are the features of post thrombotic syndrome?

Answer 5

Heavy painful calves
Pruritis 
Swelling
Varicose veins
Venous ulceration 
Brown discolouration

Post DVT - venous insufficiency - chronic venous hypertension.

Question 6

Pancytopenia, raised LDH, and hepatosplenomegaly are features of what condition?

Answer 6

Myelodysplastic syndrome

Question 7

What Are Howell jolly bodies a sign of?

Answer 7

Spleen disfunction (also see high platelets)

HJB are black bodies inside RBCs

Question 8

Malabsorption picture on blood tests plus dysfunctional spleen, in seen in which conviction

Answer 8

Coeliacs disease