Random Flashcards

1
Q

P450 Inhibitors

A

SICK FACES OMG

Sodium Valproate
Isoniazid
Cimetidine
Ketoconazole

Fluconazole
Alcohol (acute)
Clarithromycin
Erythromycin
Sulphonamides

Omeprazole
Metronidazole
Grapefruit

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2
Q

P450 Inducers

A

CRAP GPS

Carbamazepine
Rifampicin
Alcohol (chronic)
Phenytoin

Griseofulvin
Phenobarbitone
St John’s Wort

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3
Q

Phase I reactions

A

Oxidation
Reduction
Hydrolysis

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4
Q

Phase II reactions

A

Glucuronidation
Sulphation
Acetylation
Methylation

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5
Q

Oxyhemoglobin dissociation curve to RIGHT

A
Increased 2,3 DPG
Increased temp
Increased H+ (low pH)
Increased pCO2 (low pH)
Pregnancy
HbS
Altitude
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6
Q

Oxyhemoglobin dissociation curve to LEFT

A
Decreased 2,3 DPG
Decreased temp
Decreased H+ (high pH)
Decreased pCO2 (high pH)
Fetal-, carboxy-, meth- haemoglobin
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