Inhalation Agents

Question 1

Molecular Weight

Answer 1

Halo: 197
Iso: 184
En: 184
Sevo: 200
Des: 168
N2O: 44

Question 1

Chemistry

Answer 1

Hal
Iso
En
Sevo
Des
N2O

Question 2

Boiling Point

Answer 2

Halo: 50.2
Iso: 48.5
En: 56.5
Sevo: 58.5
Des: 23.5
N2O: -88

Question 3

SVP (at 20 degrees)

Answer 3

Halo: 32.3
Iso: 33.2
En: 23.3
Sevo: 22.7
Des: 89.2
N2O 5200

Question 4

Oil:Gas Coefficient

Answer 4

Halo: 224
Iso: 98
En: 98
Sevo: 53
Des: 29
N2O: 1.4

Question 5

Blood:Gas Coefficient

Answer 5

Halo: 2.3
Iso: 1.4
En: 1.8
Sevo: 0.6
Des: 0.4
N2O: 0.47

Question 6

MAC (in 100% O2)

Answer 6

Halo: 0.75
Iso: 1.17
En: 1.68
Sevo: 1.8
Des: 6.6
N2O: 103*

Question 7

MAC (in 70% N2O)

Answer 7

Halo: 0.29
Iso: 0.56
En: 0.57
Sevo: 0.66
Des: 2.5

Question 8

% Metabolised

Answer 8

Halo: 20
Iso: 0.2
En: 2
Sevo: 3-5
Des: 0.02

Question 9

Increased MAC

Answer 9

Young age
Hyperthermia
Hypernatraemia
Chronic alcohol intake
Increased sympathetic stimulation:
- MAO-I
- Acute amphetamines
- Ephedrine
- Cocaine

Question 10

Decreased MAC

Answer 10

Increasing age
Pregnancy
Hypothermia
Hyponatraemia
Hypothyroidism
Hypotension
Hypoxia
Metabolic acidosis
Acute alcohol intake
Narcotics
Ketamine
Benzodiazepines
Alpha 2 agonists
Lithium

Question 11

MAC

Answer 11

The minimum alveolar concentration of inhalation anaesthetic agent at sea level, in 100% O2, at which 50% of unpremedicated subjects (experimental animals) will fail to respond to a standard midline incision. At steady state