RANDOM Flashcards
What organisms are Gram + ?
BLCCSS (6)
Bacillus Listeria monocytogenes Clostridium Corynebacterium diphtheriae Staph Strep
What diseases are caused by Staph Aureus?
STOIC (5)
SCALDED SKIN SYNDROME: …exfoliative toxin..caused by MERSA..eats into blood system…
TOXIC SHOCK
OSTEOMYELITIS: from hospitals, locker rooms, etc
Dead bone = sequestrum
New bone = emborium
IMPETIGO (#1 Cause!!!): infection of child around mouth…“honey crusted lesion around mouth”
CARBUNCLES: many furuncles (infected hair follicles)…boils…“A carload of furuncles”
What does Staph Aureus produce?
SA produces ALPHA Toxin / Alpha Hemolysin
What tests are positive for Staph?
Catalase
Coagulase
Mannitol Salt
What diseases are caused by Strep Pyogenes?
“SERGIS” (6)
STREP THROAT
ERYSIPELAS…aka St Anthony’s Fire…superficial cellulitis
RHEUMATIC FEVER…..Jones major…See picture
Carditis (MacCallum Patch in posterior left atrium)
Syndenham’s Chorea
Subcutaneous Nodule
Erythema Marginatum
Migratory Polyarthritis
GLOMERULONEPHRITIS
IMPETIGO (#2 cause)
SCARLET FEVER…strawberry tongue… + Dicks test
What is Strep Pyogenes’ agent?
Group A Lancefield, Beta Hemolytic Strep
What is the purpose of the complement system?
Enhances phagocytosis or cellular lysis
What are the pathways of the complement system?
Classical: meet at C3B
(Ag-Ab)
Antigen Antibody
Alternative: meet at C3B
EX: Sheep’s RBCs
Lectin:
Terminal Complement Complex:
C5B-C9 = Membrane Attack Complex
Attack bacteria
Sterilization / Autoclave Pasteurization Method
274F, 121 C…..15 min
Steam heat under pressure
Denatures membranes
INEFFECTIVE against prions
Vaccination Types
Inactivated: rabies, (Salk = dead polio)
Toxoid: tetanus
Live attenuated: MMR (Sabin = active polio)
Vaccine Manufacturing
Chick Embryo = MM
Human diploid cells = Rubella, Rabies, Hep A
Monkey Kidney tissue = polio
Sequelae Vaccination
Guillian-Barre AKA Post-infectious polyradiculopathy
Ascending demyelization of PNS
Types of Studies:
Case Control = IDS risk factors
Double Blind = eliminate placebo
Restrospective = back in time
Chlamydia psittaci
Lower respiratory infection
Parrot Fever