Bacterial Diseases Flashcards

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1
Q

Yersinia pestis / Pasteurella pestis

A

Bubonic Plague ‘black death’

VECTOR: Rat flea = Xenopsylla cheopis
Arthropod Borne Bacteria

Bubos = neck and axillary lymph node enlargement
Death by asphyxiation

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2
Q

Francisella tularenis

A

Tuleremia ‘Rabit Fever’

VECTOR: Rabbits, squirrels
Arthropod Borne Bacteria

Hunters = at risk

“The French Rabbits smell Tulips”

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3
Q

Clostridium botulinum !!

A

Botulism

VECTOR: Food - meats / home canning

Neurotoxin
PREVENTS ACH RELEASE = Floppy Baby Syndrome
1st symptom = Diploplia, 2nd symptom = DEATH

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4
Q

C. jejuni !!

A

Campylobacter – Food poisoning

VECTOR: food

MCC = Gastritis
#1 symptom = diarrhea
MCC of food poisoning
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5
Q

Listeria monocytogenes

A

Listeria

VECTOR: Deli meats + soft cheeses

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6
Q

Salmonella entrides !

A

Salmonella

VECTOR: eggs + poultry

12-24 hours after ingestions = FEVER

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7
Q

Staph aureus !

A

Staphylococcus

VECTOR: Creams and Custards

2-4 hours after ingestion…NO FEVER

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8
Q

Salmonella Typhi

A

Typhoid

Rose colored spots on abdomen.
Hides in gall bladder & Peyer’s patches in Ileum
Widal Test

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9
Q

Brucella abortus

A

Brucellosis

VECTOR: Water, Milk

Bang’s disease.
Undulant fever.
Spontaneous abortions in cattle

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10
Q

Vibrio cholera

A

Cholera….”Vibrio Comma”

VECTOR: Contaminated water
wont enter bloodstream, stays in intestines

Comma shaped
Rice water stools
Vomiting

No lymph enlargement, no immune reaction

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11
Q

Shigella !!

A

Shigella

VECTOR: WATER AND SOIL BORN

Bacillary / bacterial dysentery
BLOOD IN STOOL

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12
Q

E. coli, Enterotoxigenic form !!

A

Traveler’s Diarrhea

VECTOR: Contaminated water

MONTEZUMA’S REVENGE
Enterohemorrhagic form = E. coli OH157
= Hamburger’s Disease – FATAL

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13
Q

Bacillus anthracis

A

Anthrax (Gram + Rod)

VECTORS: soil + animals

Woolsorter’s diseases
Inhaled spores (from animal hides or wools)
Zoonosis (different from cutaneous anthrax)

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14
Q

Clostridium tetani

A

Tetanus

VECTOR: Soil borne

Lockjaw aka TRISMUS
Inhibits GABA and Glycine (= blocks inhibitory NTs)

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15
Q

Clostridium perfingins

A

Gas Gangrene…..”C. Welchi”

VECTOR: Soil

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16
Q

Clostridium dificile

A

GI tract — antibody resistant

17
Q

Otitis is what? And what bacteria cause these infections?

A

EAR INFECTIONS

Otitis MEDIA
    #1  Haemophilus Influenza
    #2 Strep pneumoniae 
Otitis EXTERNA 
    #1  E. coli 
    #2 Pseudomonas aeruginosa
18
Q

Leptospira interrogans / ictohemorrhagica

A

Leptospirosis

VECTOR: Contaminated water

Spirochete
Weil’s syndrome (Hemorhhagic Jaundice)

19
Q

Borrelia Burgdorferi

A

Lyme’s Disease

VECTOR: Deer tick = Lxodes scapularis

Erythema Chronicum Migricans aka BULL’S EYE rash

20
Q

Borrelia recurrentis

A

Relapsing Fever

VECTOR: Ticks, lice, rabbits

Fever comes and goes (relapses)

21
Q

Treponema pallidum !!

A

Syphilis

VECTOR: STD

Venereal Syphilis:

  • Primary = hard painless chancre (most contagious)
  • Secondary = condylomata lata (flat warts on vulva), maculopapular rash
  • Latency = sometimes have symptoms
  • Tertiary = Gummas, neurosyphilis, Argyll Robertson pupil, Tabes Dorsalis (not contagious)
22
Q

Treponema pertenue

A

Yaws

VECTOR: Casual skin contact

Non-venereal syphilis

23
Q

What do you use to differentiate between treponema?

A

Dark Field Microscopy

24
Q

What are the 3 types of Dysentery?

A
  1. Childhood = Coxsackie Virus B
  2. Bacterial / Bacillary = Shigella
  3. Amoebic = Entamoeba Histolytica (infective stage = cyst)
25
Q

How do bacteria replicate?

A

Binary fission - asexual reproduction

26
Q

What are the bacteria types?

A

Bacilli B = Bar –> Rod Shape
Cocci C = Circle –> Round
Pleomorphic MANY SHAPES - Diphtheria= chinese letters
Rabies Bullet
Spirochete S = Spiral – Syphilis
Strep Linear
Staph Cluster
Vibrio Comma

27
Q

Name some bacterial ENZYMES that add virulence

A

B-hemolytic Strep = STREPTOKINASE (dissolves clots)
Staph
- COAGULASE (catalyses formation of fibrin from fibrinogen)
- HEMOLYSIN (breaks down RBCs)
Staph / Strep = LEUKOCIDIN
Staph / Strep / Clostridia = HYALURONIDASE

28
Q

What are the temperatures at which bacteria grow?

A

Psychrophilic = 15C or lower
Mesophilic = 25-40C….37C is optimal in humans
** Killed by FEVERS!! **
Thermophilic = 45C or above

29
Q

What is the most common cause of meningitis for newborns?

A
  1. E. Coli

2. Listeria

30
Q

What is the most common cause of meningitis for infants/kids?

A
  1. Strep pneumoniae

2. Neisseria meningitides - only one with rash

31
Q

What is the most common cause of meningitis for adults?

A

Strep pneumoniae

32
Q

What is the most LETHAL meningitis? !!!

A

Naegleria Fowleri

Causes primary amoebic meningoencephalitis

Fungus in the lungs = Cryptococcus Neoformans ***