Antibodies, Interleukins, MHC

Question 1

Antibodies: IgA

Answer 1

• Bodily secretions
• Mucous membrane (saliva, tears)
• Breast Milk
• 8 binding sites

Question 2

Antibodies: IgD

Answer 2

Helps IgG

Type 1 Hypersensitivity

Question 3

Antibodies: IgE

Answer 3

Parasitic Infections
Allergic Reactions
Hodgkins Disease = Increased Reed-Sternberg Cells
“Sneezes, wheezes, and weird ass diseases”

Question 4

Antibodies: IgG

Answer 4

FIRST to increases, SECOND exposure
Most numerous
Crosses placenta "Gee, mom, thanks!"
Anamnestic response - Never Forgets! 
IgM --> macrophages --> lymph nodes --> IgG

Question 5

Antibodies: IgM

Answer 5

Pentamer (10 binding sites) = non-specific
Largest and heaviest
FIRST to increase, FIRST exposure –> 3 months post birth, baby will make own

Question 6

What are interleukins?

Answer 6

Chemicals produced by cells

Question 7

Interleukin 1

Answer 7

Nervous System (brain)
Made by macrophages

Question 8

Interleukin 2

Answer 8

T-Cell growth factor
Made by CD4 cells
T-Helper Cell = QB of immune system (direct response)

Question 9

Interleukin 3

Answer 9

Bone Marrow + Lymph

Question 10

MHC

Answer 10

Major Histocompatibility Complex
Type 4 Sensitivity - organ/tissue rejection (self vs nonself)
T-cells = recognize MHC 1
B-cells = recognize MHC 1 & 2