Random Flashcards
New drug started 2-6 weeks ago, now with fever, rash, edema, lymphadenopathy, transminitis, eosinophilia
DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) associated with deactivation of HHV-6
Incidence of neural tube defects
0.1%, but in subsequent siblings is 2-3% if 1 sibling, and 10% if 2 siblings
Aniridia (name 3 disorders)
Lack of iris; associated with WAGR (Wilm’s tumor, Aniridia, GU malformation, Reduced IQ), albanism, ectopic lentis
Fever, weight loss, arthralgia, proximal muscle weakness, rash, elevated CK and ANA. Diagnosis?
Dermatomyositis (Rash: Hypertrophic, erythematous, pinkish lesions on dorsal IP joints = Gottron papules)
Reporting after drug adverse event/effect
No federal law requiring providers to report adverse drug reactions
Reporting after drug adverse event/effect
No federal law requiring providers to report adverse drug reactions
Sequence of primary teeth eruption
Mandibular central incisors => maxillary central incisors => maxillary lateral incisors
Familial Mediterranean fever
A.k.a. familial paroxysmal polyserositis or familial recurrent polyserositis => Mediterranean descent (Ashkenazi and Sephardic Jews, Armenians, Turks, Arabs, Greeks, Italians), Clx => fever, abdominal pain, chest pain, arthritis, FHx. Complication => amyloidosis, nephrotic syndrome/CKD. Tx => colchicine
Bloody otorrhea without hx head trauma (tx?)
Reassurance and supportive care (if trauma, must examine)
Factors for poor outcome in drowning
Asystole, submersion T > 10 min, onset of resuscitation > 10 minutes, resuscitation duration > 25 minutes (hypothermia is protective)
Stress dose steroids for adrenal crisis/insufficiency
Hydrocortisone 50 to 100 mg/m2 (do NOT need fludrocortisone because hydrocortisone will have mineralcorticoid effect)
Bronchogenic cyst (Path, Clx, diagnosis, Tx)
Caused by abnormal budding of tracheal diverticulum of foregut => bronchogenic cyst => recurrent infection, pneumothorax, malignant transformation. Get CT or MRI. Tx excision
Elevated alpha fetoprotein (AFPs) in which cancers
Liver (hepatoblastoma) and testes/scrotum (non-seminomatous germ cell tumors)
Chronic fatigue syndrome (Clx)
Overwhelming fatigue, nonrestorative sleep, sore throat, myalgia, headache, and tender points (~fibromyalgia)
Kallman syndrome (Clx and path)
Red-green color blindness, mirroring movements (involuntary movements mirroring contralateral voluntary hand movement), small dick, anosmia, midline defect, GU anomalies, senosineural hearing loss. Path => failure of GnRH producing neurons to migrate to brain with normal hypothalamic-pituitary function (normal MRI)
