Pharmacology

Question 1

Proton pump inhibitor adverse effects

Answer 1

1) Decrease absorption cations (Ca2+, Mg2+, Fe2+)
2) C. diff infection

Question 2

IVIG and vaccines

Answer 2

Live vaccines must be delayed by 8-10 months

Question 3

Teratogenic hypertensive medication

Answer 3

ACE inhibitors = cause CVS (septal defects, PDA) and CNS defects (neural tube)

Question 4

Drugs that cause gynecomastia

Answer 4

Cimetidine (PPI), spironolactone, atypical antipsychotics, TCAs, CCBs, ACEIs, ketoconizole, isoniazid, HIV meds

Question 5

Drugs that need to be taken on empty stomach

Answer 5

Drugs that need acidic environment or lack of chelators to absorb (eg. iron, levothyroxine, azole antifungals)

Question 6

Why is ciprofloxacin used for otitis externa

Answer 6

For pseudomonas aeruginosa coverage (most common cause of otitis externa)

Question 7

Medicine that causes black stool

Answer 7

Bismuth Subsalicylate and Iron