radiobiology Flashcards

1
Q

Biological effects from exposure to ionizing radiation appear to follow a _____ dose

A

linear, non threshold

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2
Q

term for the normal cellular functions and divisions that amplify the injury.

A

cellular amplification

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3
Q

The phenomenon most frequently in growing tissue exposed to radiation is the _____.

A

cessation of cell division

may be temporary or permanent

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4
Q

Time lag is referred to as _____.

A

latent period

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5
Q

____ is : immediate or early effects of radiation. Effects appear within minutes, days or weeks.

A

short term

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6
Q

____ is delayed or later effects of radiation. Effects appear within years, decades and generations later.

A

Long term

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7
Q

____ effects Appear within minutes, days or weeks after radiation exposure

A

early nonstochastic

– Severity of effect is dose related

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8
Q

___ effects on many people is cause for greater concern than the ____ effects.

A
  1. long term effects

2. Short-term effects

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9
Q

Radation exposure are those which may manifest themselves years after the original exposure

A

Long term effects

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10
Q

What are 2 types of long term effects

A
  1. Somatic damage

2. Genetic mutations

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11
Q

Name effects of somatic damage

A
  1. cancer
  2. birth defects
  3. cateracts
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12
Q

_____ may show up generations after the original radiation damage.

A

gentetic mutations

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13
Q

what are somatic dose indicatiors?

A
  1. injuries to superficial tissue
  2. Induction of cancer
  3. Cateract formation
  4. Impaired fertility
  5. Life-span shortening
  6. injuries to developing fetus
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14
Q

Somatic doses are based on measurements of the dose at specific locations which are

  1. _____
  2. ____
  3. ____
A
  1. Bone marrow
  2. Skin
  3. Thyroid
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15
Q

what are the 3 reasons in which doses are not uniformly distributed throughout the body

A
  1. Primary x-ray beam
  2. Shielding or protection

3 Natural shielding

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16
Q

What are a few of high bone marrow dose exams

A
  1. Barium enema
  2. Upper GI series
  3. Abdominal angio
17
Q

_____ refers to effects exhibited in future offspring of persons who have been irradiated

A

genetic dose

2 types:

  1. Inherited
  2. Genetic
18
Q

What are the most radiosensitve cells in the body?

A

spermatogonia

19
Q

Mature spermatozoa are quite ______.

A

radioresistant

20
Q

GSD is a function of which 3 paremters

A
  1. # of future children
  2. X-ray exam rate
  3. Mean gonad dose per exam
21
Q

The ____ GSD, the ___ number of mutations.

A
  1. lower

2. Lower

22
Q

Radiation induced cancers occur in which parts of the body:

A
  1. Female breast
  2. Thyroid gland
  3. Hemopoietic tissue
  4. Lungs
  5. GI tract
  6. Bones