Radiation Injury

Question 1

ionizing radiation long term effect

Answer 1

fibrosis >6 weeks

and vascular damage- surgeons won’t do surgery because wounds won’t do as well

Question 2

long term effects on organ

Answer 2

squamous cell carcinoma

osteosarcoma, angiosarcoma

Question 3

body systems in rank from most vulnerable to least from radiation

Answer 3

hematopoietic system (bone marrow, spleen, ln)

GI system
CNS

Question 4

Acute radiation syndromes

Answer 4

molecular death (>100,000 Rad) 
CNS syndrome (>2000 RAD)
GI syndrome (500-2000)
Hematopoietic syndrome (50-500) 
Prodromal syndrome with possible late effects (years later) (<50)

Question 5

Hematopoietic syndrome

Answer 5

50-500 RAD
nausea, vomiting diarrhea, resolves in 1-2 days
bone marrow transplant is tx
late effects- observe for development of post radiation cancers

Question 6

GI syndrome

Answer 6

death results in few days from circulatory collapse
no tx except for those with lower radiation doses that might benefit from bone marrow transplant
NVD

Question 7

What syndrome can be treated?

Answer 7

hematopoietic- hla typing, bmt

Question 8

radioactive fallout

Answer 8

coarse particles caught in explosion fall out near site of blast