Racemic Epinephrine

Question 1

Brand Names

Answer 1

S2, AsthmaNefrin

Question 2

Drug Classification

Answer 2

Alpha/Beta Agonist

Question 3

Mechanism of Action

Question 4

Indications

Answer 4

Bronchospasm from either: Croup with stridor at rest; OR Bronchiolitis patients who do not respond to suctioning or for impending respiratory failure

Question 5

Contraindications

Answer 5

Epiglottitis

Question 6

Side effects / Precautions

Answer 6

Tachycardia, arrythmias, restlessness, headache, nausea, sweating, tremors, angina

Question 7

Adult Dose

Answer 7

11.25mg/0.5 mL (2.25%) mixed with 3mL NaCl

Question 8

Pediatric Dose

Answer 8

0.5 ml of 2.25% (11.25mg) mixed with 3 mL 0.9% NaCl
If <4 years old: 0.05 mL/kg of 2.25% solution
(1.125% dextro-epinephrine and 1.125% levo-epinephrine)

Question 9

Max adult dose (max pedi dose)

Answer 9

11.25mg/0.5mL (11.25mg/0.5mL)

Question 10

Onset of Action

Answer 10

1-5 minutes

Question 11

Duration of Effects

Answer 11

1-3 hours

Question 12

Routes of Administration

Answer 12

Inhalation / Nebulized