Ondansetron Flashcards
1
Q
Brand Name
A
Zofran
2
Q
Drug Classification
A
Anti-emetic
3
Q
Mechanism of Action
A
5 HT3 receptor antagonist; Ondansetron will block the effects of serotonin in the vagal afferents in the GI system and in the central vomiting system; serotonin is a neurotransmitter that may cause nausea and vomiting; so inhibiting these receptors will lead to anti-emetic effects
4
Q
Indications
A
Nausea, vomiting
5
Q
Contraindications
A
Hypersensitivity, coadministration with apomorphine (Parkinson’s medication)
6
Q
Side Effects / Precautions
A
Headache, fatigue, constipation, dizziness
7
Q
Adult Dose
A
4 mg PO, IV/IO
8
Q
Pediatric Dose
A
0.1 mg/kg IV/IO
9
Q
Max Dose Adult (Peds)
A
4 mg (4 mg)
10
Q
Onset of Action
A
30 minutes
11
Q
Duration of Effects
A
6 hours
12
Q
Routes of Administration
A
IV/IO, PO if >5 years old
