Rabies Flashcards

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1
Q

Biological systems affected

A

Nervous system

Respiratory system

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2
Q

Pathogen

A

Rhabdovirus (lyssavirus)

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3
Q

Other key notes

A

Can infect humans
Clinical signs depend on immune status, virus dose and location of bite
Virus replicates in muscles before entering nervous system
Once in nervous, prognosis is death

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4
Q

Prevention

A

Vaccination

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5
Q

Route of transmission

A

Direct contact with saliva from bite wounds

Incubation between 1-6 months

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6
Q

Key physical symptoms

A
Furious:
Hyperexcitability with periods of calm
Pica
Aggression at unseen objects
Ataxia
Progressive facial paralysis
Drooling
Dysphagia
Frothy saliva and convulsions

Dumb:
Timid
Affectionate
Generalised paresis leading to paralysis and ataxia
Respiratory muscles become paralysed
Lesions present in brain in diagnosis after death

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7
Q

Possible treament options

A

Euthanasia

DEFRA must be alerted

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