RA

Question 1

Frequent hallmark of RA

Answer 1

Tendon flexor tenosynovitis

Question 2

Piano key movement involved tendons

Answer 2

Ulnar styloid and extensor carpi ulnaris

Question 3

MC cause of death RA patients

Answer 3

Ischemic heart disease

Followed by infection

Question 4

Primary determinant of disease

1. Early
2. Late

Answer 4

Early= extent of joint inflammation
Late= amount of joint damage

Question 5

DMaRD of choice for RA

Answer 5

Methotrexate

Question 6

Show. To retard progression of hoint disease

Answer 6

Low dose steroids

Question 7

Rx ofnglucocoryicoid induced osteoporosis

Answer 7

Bisphosphonate

Question 8

Inhibitor of pyrimidine synthesis

Similar efficacy to MXT

Answer 8

Leflunomide

Question 9

Initial radiographic finding in RA

Answer 9

Periarticular osteopenia

Question 10

Caused by subluxation of MCP joints

Answer 10

Ulnar deviation

Question 11

Occur in Px with highest levels of disease activity

Answer 11

Subcutaneous nodules

Question 12

MC valvular involvement in RA

Answer 12

MR

Question 13

Felty’s syndrome

Answer 13

SNR
Splenomegaly
Neutropenia
RA (nodular)

Question 14

MC cause death in RA

Answer 14

CV disease

Question 15

Sex hormones in RA

Answer 15

hypoandrogenism
- lower mean serum testoserone
- low LH
and low DHEA levels

Question 16

Most reproducible environmental link to RA

Answer 16

cigarette smoking

Question 17

Pathologic hallmarks of RA

Answer 17

synovial inflammation and proliferation with focal bone erosions