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Rheuma > Biologics > Flashcards

Biologics Flashcards

1
Q

Fusion protein containing TNF receptor bound to human IgG

A

Etanercept

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2
Q

Recombinant form of IL1 antagonist

A

Anakinra

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3
Q

Fusion protein CTLA-4

Inhibits co stimulation of T cells by blocking CD28 CD20 interactions

A

Abatacept

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4
Q

Inhibits JAK1 and JAK3

A

Tofacinib

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5
Q

Soluble IL6 receptor inhibitor

A

Tocilizumab

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6
Q

Chimeric monoclonal antibody TNFa inhibitor

A

Infliximab

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7
Q

Humanized monoclonal antibody

TNFa inhibitor

A

Adalimumab

Golimumab

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8
Q

Inhibitor of pyrimidine synthesis (similar effect as methotrexate)

A

Leflunomide

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9
Q

In psoriatic arthritis

a monoclonal antibody to the shared IL23/ IL 12p40 subunit

A

Ustekinumab

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10
Q

Anti IL7 in PSA

A

Secukinumab

Brodalimumab

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11
Q

IL 5 antibody used in RosinophilicbGranulomatosis with polyangiitis

A

Mepolizumab

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12
Q

PEGylated TNF alpha

A

Certolizumab

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Rheuma (10 decks)

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