RA Flashcards
1
Q
Features RA
A
RHEUMATISM rheumatoid factor positive HLA DR 1,4 ESR raised ulnar deviation fingers morning stiffness, MCP + PIP swelling atlanto-axial joint subluxation, ankylosis t cells inflammed synovium (pannus) swan neck, boutonniere, z-deformity thumb muscle wastage small muscles hand
2
Q
xray RA
A
JESS joint space loss symmetrical, joint deformities erosion joint synovial thickening subluxation
LESS Loss of joint space Erosions Soft tissue Swelling Soft bones (osteopenia)
3
Q
diagnostic criteria RA
A
ARMS >4/7 arthritis >3 joints / hands / symmetrical rheumatoid nodules, radiographic changes morning stiffness >1 hour serum rheumatoid factor
4
Q
RA tx
A
DMARDS: most sufferers can get appropriate pain control methotrexate sulfasalazine ciclosporin gold azathioprine penicillamine hydroxyChloroquine
5
Q
RA hands
A
MCP volar subluxation MCP ulnar deviation wrist subluxation symmetrical deforming polyarthropathy swan neck, boutonniere, z-thumb rheumatoid nodules muscle wasting = disuse atrophy scar carpal tunnel
6
Q
RA systemic
A
lungs: effusion, fibrosis, bronchiolitis, Caplan nodules
eyes: dry Sjogren, scleritis
neuro: peripheral neuropathy
haem: Felty, anaemia
cardiac: pericarditis
renal: nephrotic syndrome
7
Q
Felty’s what is
A
SANTA Splenomegaly Anaemia Neutropenia Thrombocytopenia Arthritis (rheumatoid)
