Quiz 7 Flashcards

1
Q

What is the role of parietal cells?

A

stomach cells that secrete HCl

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2
Q

____________ is activated by HCl secretion and released from chief epithelial cells

A

pepsin

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3
Q

The stomach protects itself from acid by secreting ______

A

HCO3

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4
Q

Microbes use the __________-__________ acid resistant system when exposed to very low pH

A

glutamine-dependent
** not always on

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5
Q

When the GLU-dependent acid resistance system is turned on glutamine is brought into the cell via the ______ transporter

A

GadC

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6
Q

When the GLU-dependent acid resistance system is turned on glutamine is converted into ________

A

GABA (converts a proton into CO2)

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7
Q

most microbes only have Gad___ that converts GLU into GABA

A

GadB

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8
Q

What virus can with stand very low pH?

A

HIV

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9
Q

______ & _______ on H. pylori helps it attach to epithelial cells

A

BabA & SabA

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10
Q

How does the multiple flagella of H/ pylor aid it?

A

swims through mucus layer

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11
Q

What medication can cause increased bacterial overgrowth?

A

proton-pump inhibitor

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12
Q

___________ is present throughout the whole large intestine

A

glycocalyx

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13
Q

The majority of commensals are coated in _____

A

IgA

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14
Q

What is a intracellular PRR?

A

NOD1&2

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15
Q

A type I immune response is TH___, what are the cytokines?

A

TH1
IL-12, 18, IFN-g

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16
Q

A type II immune response is TH___, what are the cytokines?

A

TH2
IL-3, 4, 5, 9, 13

17
Q

What TH2 cell’s cytokine is an alarmin?

A

IL-33

18
Q

A type III immune response is TH___, what are the cytokines?

A

TH17
IL-23, 6, 1, 17, 22

19
Q

Ig___ opsonizes bacteria in a type _____ reaction

A

IgG
type III