Quiz 7 Flashcards
What is the role of parietal cells?
stomach cells that secrete HCl
____________ is activated by HCl secretion and released from chief epithelial cells
pepsin
The stomach protects itself from acid by secreting ______
HCO3
Microbes use the __________-__________ acid resistant system when exposed to very low pH
glutamine-dependent
** not always on
When the GLU-dependent acid resistance system is turned on glutamine is brought into the cell via the ______ transporter
GadC
When the GLU-dependent acid resistance system is turned on glutamine is converted into ________
GABA (converts a proton into CO2)
most microbes only have Gad___ that converts GLU into GABA
GadB
What virus can with stand very low pH?
HIV
______ & _______ on H. pylori helps it attach to epithelial cells
BabA & SabA
How does the multiple flagella of H/ pylor aid it?
swims through mucus layer
What medication can cause increased bacterial overgrowth?
proton-pump inhibitor
___________ is present throughout the whole large intestine
glycocalyx
The majority of commensals are coated in _____
IgA
What is a intracellular PRR?
NOD1&2
A type I immune response is TH___, what are the cytokines?
TH1
IL-12, 18, IFN-g