Quiz 6 #1 Antianginals Flashcards
Role of coronary arteries
Arteries that deliver oxygen to the heart muscle
Types of Angina
1) chronic stable angina (also known as classic or exertional angina)
2) variant angina (also known as Prinzmetal’s or vasospastic angina)
3) unstable angina.
Nitro Instructions
1 pill every 5 minutes, if first pill did not resolve chest pain, call 911 as taking the second pill
*Max of 3 pills always 5 mins apart
Angina definition and cause
Sudden pain beneath the sternum, often radiating to the left shoulder, left arm, and jaw.
Anginal pain is precipitated when the oxygen supply to the heart is insufficient to meet oxygen demand. Occurs secondary to atherosclerosis of coronary arteries.
Contrast “rescue” and “controller” drugs
Controller drugs:
Beta-blockers, calcium channel blockers, and long-acting nitrates provide baseline prophylaxis or protection against acute angina attacks
Rescue drugs:
Sublingual (SL), translingual spray, and intravenous (IV) nitroglycerin is used to treat acute anginal pain
Nitroglycerin Tolerance
Occurs in patients taking nitrates around the clock or with long-acting forms.
Prevented by allowing a regular nitrate-free period to allow enzyme pathways to replenish.
Nitrates MOA/Drug Effects
MOA: NTG dilates veins which reduces venous return (↓ preload).
Effects: Decreased cardiac oxygen demand (atherosclerosis heart disease) and increased cardiac oxygen supply (variant angina)
Nitrates Indications
Stable, unstable, and variant angina
Nitrates Contraindications
Hypotension, erectile dysfunction drugs (e.g. Viagra, Levitra, or Cialis)
Nitrates Adverse Effects
Headache
Orthostatic hypotension
Reflex tachycardia
Tolerance
Nitrates Patient Education
- Instruct proper technique for administering SL, transdermal patch ointment, or oral routes
- Manage headache with acetaminophen
- Instruct men not to take with ED drugs (lethal combo!)
Beta Blockers MOA/Drug Effects
MOA: Prevent stimulation of beta receptors in the heart which decreases heart rate and contractility. Also prevents release of renin.
Effect: Decreased myocardial oxygen demand
Beta Blockers Indications
Prevention/prophylaxis of stable angina
Beta Blockers Nursing Implications
Assess vital signs – hold and notify MD for HR less than 60
Review Calcium Channel Blockers and Beta Blockers
I left some of the stuff we’ve done, out of the cards